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糖化血红蛋白的自动比色测定

Automated colorimetric estimation of glycosylated haemoglobins.

作者信息

Burrin J M, Worth R, Ashworth L A, Currie S, Alberti K G

出版信息

Clin Chim Acta. 1980 Sep 8;106(1):45-50. doi: 10.1016/0009-8981(80)90373-3.

Abstract

The measurement of glycosylated haemoglobin is now widely used as a guide to glycaemic control in patients with diabetes mellitus. Present methods for measurement of glycosylated haemoglobin are either laborious, expensive or both. We describe a precise and inexpensive method for the automated analysis of glycosylated haemoglobin based on a colorimetric technique. The within-batch coefficient of variation ranged from 2.0 to 4.8% and between-batch was less than 11.0%. At least 200 samples can be analysed per day.

摘要

糖化血红蛋白的测定现已广泛用于指导糖尿病患者的血糖控制。目前测定糖化血红蛋白的方法要么费力、要么昂贵,或者两者兼具。我们描述了一种基于比色技术的精确且廉价的糖化血红蛋白自动分析方法。批内变异系数在2.0%至4.8%之间,批间变异系数小于11.0%。每天至少可分析200个样本。

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