Gokal R, McHugh M, Fryer R, Ward M K, Kerr D N
Br Med J. 1980 Aug 16;281(6238):474-7. doi: 10.1136/bmj.281.6238.474.
Thirty-two patients aged 8-63 years trained to manage themselves by continuous ambulatory peritoneal dialysis for end-stage renal failure achieved better steady-state serum biochemistry and much higher haemoglobin and lower serum phosphate concentrations than during treatment with haemodialysis up to one year before. Two patients, however, returned to intermittent haemodialysis because of recurrent peritonitis. Costs of the technique during the first year were less than half those incurred in the first year of home haemodialysis. Nevertheless, the major advantage was the ease with which patient independence and rehabilitation could be achieved. This technique is an appreciable advance over other forms of management for end-stage renal failure. Nevertheless, until it is more refined and long-term problems have been assessed it should probably be used only in established renal units where back-up treatments are available.
32例年龄在8至63岁之间的患者接受了持续性非卧床腹膜透析培训,以自我管理终末期肾衰竭,与一年前进行血液透析治疗期间相比,他们实现了更好的稳态血清生化指标,血红蛋白水平更高,血清磷酸盐浓度更低。然而,有两名患者因反复发生腹膜炎而恢复了间歇性血液透析。该技术第一年的成本不到家庭血液透析第一年成本的一半。尽管如此,其主要优势在于能够轻松实现患者的独立和康复。与终末期肾衰竭的其他管理形式相比,这项技术有显著进步。然而,在其更加完善且长期问题得到评估之前,可能仅应在有备用治疗手段的成熟肾脏科室使用。