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睾酮与实验大鼠社会探究行为的持续性

Testosterone and persistance of social investigation in laboratory rats.

作者信息

Thor D H

出版信息

J Comp Physiol Psychol. 1980 Oct;94(5):970-6. doi: 10.1037/h0077831.

DOI:10.1037/h0077831
PMID:7430478
Abstract

In a series of experiments, mature male and female rats were individually exposed in their home cages to sexually immature conspecifics. A prominent sex difference was observed in duration of social investigation prior to a criterion of neglect. When pups were 5 days of age, no sex difference was observed, but when pups were 8 days of age and older, mature males consistently investigated them for significantly longer intervals than did mature females. Furthermore, intact males investigated prepuberal conspecifics for significantly longer intervals than did castrated males, castrated females, or intact females; none of the latter three groups differed significantly from each other. Following testosterone treatment, castrated males investigated unfamiliar, prepuberal conspecifics for a significantly longer duration than did untreated castrated control animals. The combined results support the conclusion that gonadal testosterone effects a greater perseveration of social investigation in males.

摘要

在一系列实验中,将成年雄性和雌性大鼠分别置于其饲养笼中,使其接触性未成熟的同种个体。在达到忽视标准之前的社会调查持续时间上,观察到了显著的性别差异。当幼崽5日龄时,未观察到性别差异,但当幼崽8日龄及以上时,成年雄性对它们的调查持续时间始终显著长于成年雌性。此外,完整雄性对青春期前同种个体的调查持续时间显著长于去势雄性、去势雌性或完整雌性;后三组之间没有显著差异。睾酮治疗后,去势雄性对陌生的青春期前同种个体的调查持续时间显著长于未治疗的去势对照动物。综合结果支持这样的结论:性腺睾酮会使雄性在社会调查中表现出更强的坚持性。

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