一种采用计算机程序的DNA测序策略。
A strategy of DNA sequencing employing computer programs.
作者信息
Staden R
出版信息
Nucleic Acids Res. 1979 Jun 11;6(7):2601-10. doi: 10.1093/nar/6.7.2601.
Abstract
With modern fast sequencing techniques and suitable computer programs it is now possible to sequence whole genomes without the need of restriction maps. This paper describes computer programs that can be used to order both sequence gel readings and clones. A method of coding for uncertainties in gel readings is described. These programs are available on request.
摘要
借助现代快速测序技术和合适的计算机程序，现在无需限制图谱就能对整个基因组进行测序。本文描述了可用于对序列凝胶读数和克隆进行排序的计算机程序。还描述了一种对凝胶读数中的不确定性进行编码的方法。这些程序可应要求提供。
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