Suppr超能文献

类风湿关节炎患者的血浆锌及其与临床症状和药物治疗的关系

Plasma zinc and its relationship to clinical symptoms and drug treatment in rheumatoid arthritis.

作者信息

Balogh Z, El-Ghobarey A F, Fell G S, Brown D H, Dunlop J, Dick W C

出版信息

Ann Rheum Dis. 1980 Aug;39(4):329-32. doi: 10.1136/ard.39.4.329.

DOI:10.1136/ard.39.4.329
PMID:7436558
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1000551/
Abstract

Total plasma zinc levels in patients with rheumatoid arthritis on different therapeutic treatments were determined in conjunction with total serum proteins, serum albumin and globulin, and articular index of joint tenderness, erythrocyte sedimentation rate, rheumatoid factor, serum copper, and serum iron. There were significantly lower zinc levels in patients with rheumatoid arthritis on nonsteroidal anti-inflammatory drugs than in patients on levamisole and penicillamine. Zinc levels correlated positively with serum albumin, and there was an inverse correlation between zinc levels and both ESR and globulin concentration in all rheumatoid patients. However, the correlation coefficient varied in the different treatment groups. The results of this study support the hypothesis that low plasma zinc level in rheumatoid arthritis is one of the nonspecific features of inflammation.

摘要

测定了接受不同治疗的类风湿性关节炎患者的血浆总锌水平，并同时测定了总血清蛋白、血清白蛋白和球蛋白、关节压痛的关节指数、红细胞沉降率、类风湿因子、血清铜和血清铁。使用非甾体抗炎药治疗的类风湿性关节炎患者的锌水平显著低于使用左旋咪唑和青霉胺治疗的患者。锌水平与血清白蛋白呈正相关，在所有类风湿性关节炎患者中，锌水平与红细胞沉降率和球蛋白浓度均呈负相关。然而，不同治疗组的相关系数有所不同。本研究结果支持以下假设：类风湿性关节炎患者血浆锌水平低是炎症的非特异性特征之一。

相似文献

1
Plasma zinc and its relationship to clinical symptoms and drug treatment in rheumatoid arthritis.类风湿关节炎患者的血浆锌及其与临床症状和药物治疗的关系
Ann Rheum Dis. 1980 Aug;39(4):329-32. doi: 10.1136/ard.39.4.329.
2
A review of the effects of levamisole on erythrocyte sedimentation rate, acute phase proteins, and anemia.左旋咪唑对红细胞沉降率、急性期蛋白和贫血影响的综述。
J Rheumatol Suppl. 1978;4:43-7.
3
Treatment of rheumatoid arthritis with levamisole.用左旋咪唑治疗类风湿性关节炎。
Agents Actions Suppl. 1980;7:55-7.
4
[Chlorbutin, azathioprine, D-penicillamine and levamisole (decaris) in the treatment of patients with rheumatoid arthritis. IV. Comparative evaluation of their effects on systemic (extra-articular) manifestations of the disease].[氯丁因、硫唑嘌呤、D-青霉胺和左旋咪唑（驱虫净）治疗类风湿性关节炎患者。IV. 它们对该疾病全身（关节外）表现的作用的比较评估]
Ter Arkh. 1985;57(8):44-52.
5
Serum copper and its relationship to clinical symptoms in rheumatoid arthritis.类风湿关节炎患者血清铜及其与临床症状的关系。
Ann Rheum Dis. 1979 Apr;38(2):174-6. doi: 10.1136/ard.38.2.174.
6
Serum zinc and copper in active rheumatoid arthritis: correlation with interleukin 1 beta and tumour necrosis factor alpha.活动期类风湿关节炎患者血清锌和铜水平：与白细胞介素1β及肿瘤坏死因子α的相关性
Clin Rheumatol. 1998;17(5):378-82. doi: 10.1007/BF01450895.
7
The effect of drugs on serum histidine levels in rheumatoid arthritis.药物对类风湿关节炎患者血清组氨酸水平的影响。
Rheumatol Int. 1983;3(4):145-9. doi: 10.1007/BF00541592.
8
Controlled multicenter trial of tiopronin and d-penicillamine for rheumatoid arthritis.硫普罗宁与青霉胺治疗类风湿关节炎的对照多中心试验。
Arthritis Rheum. 1982 Aug;25(8):923-9. doi: 10.1002/art.1780250803.
9
Relationship between erythrocyte sedimentation rate and serum C-reactive protein in rheumatoid arthritis.类风湿关节炎中红细胞沉降率与血清C反应蛋白之间的关系。
Ann Rheum Dis. 1979 Aug;38(4):362-3. doi: 10.1136/ard.38.4.362.
10
Does second-line therapy affect the radiological progression of rheumatoid arthritis?二线治疗是否会影响类风湿关节炎的影像学进展？
Ann Rheum Dis. 1984 Feb;43(1):18-23. doi: 10.1136/ard.43.1.18.

引用本文的文献

1
The comprehensive relationship between combined anti-inflammatory and healthy diets and all-cause mortality in rheumatoid arthritis: results from NHANES 2003-2018.类风湿关节炎中联合抗炎与健康饮食和全因死亡率之间的综合关系：2003 - 2018年美国国家健康与营养检查调查结果
Arthritis Res Ther. 2024 Dec 23;26(1):226. doi: 10.1186/s13075-024-03462-y.
2
Subjective Symptoms and Disease Activity Related to Serum Zinc Concentration in Primary Sjögren's Syndrome.原发性干燥综合征中主观症状及疾病活动与血清锌浓度的关系
J Clin Med. 2024 Aug 9;13(16):4672. doi: 10.3390/jcm13164672.
3
Zinc Status and Autoimmunity: A Systematic Review and Meta-Analysis.锌的状态与自身免疫：系统评价和荟萃分析。
Nutrients. 2018 Jan 11;10(1):68. doi: 10.3390/nu10010068.
4
A pilot study on zinc levels in patients with rheumatoid arthritis.类风湿关节炎患者锌水平的初步研究。
Biol Trace Elem Res. 2011 Nov;143(2):854-62. doi: 10.1007/s12011-010-8952-2. Epub 2011 Jan 29.
5
Copper and zinc body levels in inflammation: an overview of the data obtained from animal and human studies.炎症状态下铜和锌的体内水平：来自动物和人体研究的数据综述
Agents Actions. 1993 Jul;39(3-4):195-209. doi: 10.1007/BF01998974.
6
Another look at zinc.再看锌。
Br Med J (Clin Res Ed). 1981 Apr 4;282(6270):1098-9.
7
Zinc sulphate in rheumatoid arthritis.类风湿关节炎中的硫酸锌
Ann Rheum Dis. 1982 Oct;41(5):456-7. doi: 10.1136/ard.41.5.456.
8
Nutritional status in patients with rheumatoid arthritis.类风湿关节炎患者的营养状况
Ann Rheum Dis. 1984 Jun;43(3):386-90. doi: 10.1136/ard.43.3.386.
9
Reduced zinc in peripheral blood cells from patients with inflammatory connective tissue diseases.炎症性结缔组织病患者外周血细胞中锌含量降低。
Inflammation. 1985 Jun;9(2):189-99. doi: 10.1007/BF00917591.
10
Predictive clinical and laboratory parameters for serum zinc and copper in rheumatoid arthritis.类风湿关节炎患者血清锌和铜的预测性临床及实验室参数
Ann Rheum Dis. 1988 Oct;47(10):816-9. doi: 10.1136/ard.47.10.816.

本文引用的文献

1
Studies on zinc in blood II.血液中锌的研究 二
Scand J Clin Lab Invest. 1951;3 Suppl. 2:1-74.
2
WHOLE-BLOOD CONCENTRATIONS OF COPPER AND ZINC IN RHEUMATOID ARTHRITIS STUDIED BY ACTIVATION ANALYSIS.通过活化分析研究类风湿性关节炎患者血液中铜和锌的全血浓度。
Acta Rheumatol Scand. 1965;11:30-4. doi: 10.3109/rhe1.1965.11.issue-1-4.05.
3
Serum-potassium levels as an index of body content.血清钾水平作为身体钾含量的指标。
Lancet. 1957 Mar 2;272(6966):458-9. doi: 10.1016/s0140-6736(57)90525-1.
4
Comparative metabolism of copper and zinc in patients with Wilson's disease (hepatolenticular degeneration).威尔逊病（肝豆状核变性）患者铜和锌的代谢比较
Am J Med Sci. 1967 Jul;254(1):13-23. doi: 10.1097/00000441-196707000-00002.
5
The effect of chrysotherapy on trace metals in patients with rheumatoid arthritis.金疗法对类风湿关节炎患者体内微量元素的影响。
Arthritis Rheum. 1971 Jul-Aug;14(4):533-8. doi: 10.1002/art.1780140413.
6
Binding of zinc to amino acids and serum proteins in vitro.锌在体外与氨基酸及血清蛋白的结合
J Lab Clin Med. 1970 Sep;76(3):416-25.
7
Effect of zinc deficiency on collagen metabolism.锌缺乏对胶原蛋白代谢的影响。
J Lab Clin Med. 1971 Nov;78(5):853.
8
The computed distribution of copper(II) and zinc(II) ions among seventeen amino acids present in human blood plasma.人体血浆中十七种氨基酸中铜（II）离子和锌（II）离子的计算分布情况。
Biochem J. 1971 Feb;121(3):549-55. doi: 10.1042/bj1210549.
9
Competition for zinc among serum albumin and amino acids.血清白蛋白与氨基酸之间对锌的竞争。
Biochim Biophys Acta. 1972 Jun 26;273(1):64-72. doi: 10.1016/0304-4165(72)90191-2.
10
The effect of zinc and other metals on the stability of lysosomes.锌及其他金属对溶酶体稳定性的影响。
Proc Soc Exp Biol Med. 1972 Jun;140(2):642-6. doi: 10.3181/00379727-140-36521.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验