Lund N, Odman S, Lewis D H
Acta Anaesthesiol Scand. 1980 Jun;24(3):155-60. doi: 10.1111/j.1399-6576.1980.tb01525.x.
The MDO (Mehrdraht Dortmund Oberfläche) oxygen electrode was used for studies of oxygen pressure fields in rat skeletal muscle. With this multiwire oxygen electrode, the three-dimensional oxygen pressure field was measured and presented as a two-dimensional frequency distribution, i.e., a histogram. Statistical analysis of the histograms was carried out with the two-sample Kolmogorov-Smirnov test. This eliminated the influence of mean values, since these do not always represent the actual biological situation. The oxygen pressure fields in skeletal muscle of anesthetized normal rats breathing air spontaneously were investigated. When the oxygen pressure in the inspired gas was changed (50% and 95%), changes were seen in muscle oxygen pressure curves. The normal oxygen pressure field histograms were compared with those obtained after local anesthesia, after local trauma to the muscle and after hemorrhage. After local anesthesia the histograms were unchanged. Significant changes in the distribution types of the histograms were found after trauma in all rats studied. After hemorrhage significant changes, similar to those seen after trauma, were found in 15 of the 23 rats studied. Local blood flow was also measured with the 133xenon-clearance method in the hemorrhage experiments. No correlation was found between the changes in the mean oxygen tension values and the changes in 133xenon-clearance.
MDO（多特蒙德多丝表面）氧电极用于研究大鼠骨骼肌中的氧分压场。使用这种多丝氧电极测量三维氧分压场，并将其呈现为二维频率分布，即直方图。使用双样本柯尔莫哥洛夫-斯米尔诺夫检验对直方图进行统计分析。这消除了平均值的影响，因为平均值并不总是代表实际的生物学情况。对自主呼吸空气的麻醉正常大鼠骨骼肌中的氧分压场进行了研究。当吸入气体中的氧分压发生变化（50%和95%）时，肌肉氧分压曲线出现变化。将正常氧分压场直方图与局部麻醉后、肌肉局部创伤后和出血后的直方图进行比较。局部麻醉后直方图无变化。在所有研究的大鼠中，创伤后直方图的分布类型均有显著变化。在23只研究大鼠中的15只中，出血后发现了与创伤后相似的显著变化。在出血实验中还使用133氙清除法测量了局部血流量。未发现平均氧张力值的变化与133氙清除率的变化之间存在相关性。
