Taylor R H, Bagley F H, Braasch J W, Warren K W
Am J Surg. 1981 Jan;141(1):28-33. doi: 10.1016/0002-9610(81)90007-6.
We report a 10 year review comparing the results of pain relief after three procedures for chronic pancreatitis: Whipple pancreatoduodenectomy, modified Puestow side-to-side longitudinal pancreaticojejunostomy and distal pancreatic resection. Results of follow-up review at 6 months, 2 years and 5 years were tabulated. Five year follow-up data were available on more than 80 percent of patients. The proportion of good results for pain relief decreased with the passage of time regardless of the procedure performed. Although equally good results are obtained after either pancreatoduodenectomy or pancreaticojejunosotomy, we conclude that in the presence of a dilated duct, the procedure of choice is pancreaticojejunostomy. If the duct is not dilated, we then favor pancreatoduodenectomy, after which the pain relief is significantly better (p = 0.05) than after distal resection. Our data show that, for all factors evaluated, the poorest pain relief was obtained after distal resection. Therefore that procedure has limited value when used specifically for relief of pain in chronic pancreatitis, except in the uncommon circumstance when the disease is confined to the distal part of the gland. Our study also shows that patients who have more radical distal resection have no better pain relief than those who have 50 percent distal resection.
我们报告了一项为期10年的回顾性研究,比较了慢性胰腺炎三种手术(惠普尔胰十二指肠切除术、改良普斯托侧侧纵向胰空肠吻合术和胰腺远端切除术)后的疼痛缓解结果。将6个月、2年和5年的随访结果制成表格。超过80%的患者有5年随访数据。无论采用何种手术方式,随着时间推移,疼痛缓解的良好结果比例均下降。虽然胰十二指肠切除术或胰空肠吻合术后均可获得同样良好的结果,但我们得出结论,在存在胰管扩张的情况下,首选手术方式为胰空肠吻合术。如果胰管未扩张,我们则倾向于胰十二指肠切除术,术后疼痛缓解明显优于胰腺远端切除术(p = 0.05)。我们的数据表明,就所有评估因素而言,胰腺远端切除术后疼痛缓解最差。因此,该手术专门用于缓解慢性胰腺炎疼痛时价值有限,除非在罕见情况下疾病局限于胰腺远端。我们的研究还表明,进行更广泛胰腺远端切除术的患者与进行50%胰腺远端切除术的患者相比,疼痛缓解情况并无更好。