Althesin infusion and regional blockade anaesthesia for major gynaecological surgery.

The effects of an infusion of a 10% Althesin solution to induce sleep in patients undergoing major gynaecological surgery performed under extradural analgesia are presented. There was no significant depressant effect on the cardiovascular system, but a predictable and preventable depression of respiratory function. Liver function tests were unaffected by the infusion. Operating conditions were satisfactory in all patients and postoperative recovery was smooth and uncomplicated.