Nunes V L, Dorval M E, Oshiro E T, Noguchi R C, Arão L B, Hans Filho G, Espíndola M A, Cristaldo G, da Rocha H C, Serafini L N
Centro de Ciências Biológicas e da Saúde, Universidade Federal de Mato Grosso do Sul (UFMS), Brasil.
Rev Soc Bras Med Trop. 1995 Jul-Sep;28(3):185-93. doi: 10.1590/s0037-86821995000300004.
A study on the resident population of 150 inhabitants of Boa Sorte in the Municipality of Corguinho, Mato Grosso do Sul State, Brazil was made, from March 1991 to March 1994, to establish the prevalence of South American Cutaneous Leishmaniasis (SACL), and to characterize the affected population, in an area of recent transmission. Twelve of the inhabitants showed lesions suspected to be SACL, and in 8 cases it was possible to confirm this by biopsy and parasitology. The mucosal form was found in one patient only, the rest showed the following cutaneous forms: ulcerated (3), ulcero-verrucose (1), hyperkeratotic ulcer (1), infiltrated maccule (1), nodule with florid regional adenopathy (1). All patients reacted favorably to treatment with glucantime, with lesion scarring. Side-effects were rare. The parasite isolated from all patients was identified as Leishmania (Viannia) braziliensis. The Montenegro skin test, applied to the 150 inhabitants, showed 32 reactive ones. Of these, six were carriers of the disease, 21 showed sequelae suggestive of the disease and five showed no signs of infection. The age grouping of the cohort ranged from 22 to 78 years, 75% being male. To date, transmission is suspected to be in the peridomicile.
1991年3月至1994年3月，对巴西南马托格罗索州科尔吉尼奥市博阿索尔蒂的150名居民常住人口进行了一项研究，以确定南美皮肤利什曼病（SACL）的患病率，并对近期传播地区的受影响人群进行特征描述。12名居民出现疑似SACL的病变，其中8例通过活检和寄生虫学得以确诊。仅1例患者出现黏膜型，其余患者表现为以下皮肤型：溃疡型（3例）、溃疡疣状型（1例）、角化过度溃疡型（1例）、浸润性斑疹型（1例）、伴有明显局部淋巴结病的结节型（1例）。所有患者对葡糖胺治疗反应良好，病变形成瘢痕。副作用罕见。从所有患者分离出的寄生虫被鉴定为巴西利什曼原虫（维安亚利什曼原虫）。对这150名居民进行的蒙氏皮肤试验显示，32人呈阳性反应。其中，6人患有该病，21人有提示该病的后遗症，5人无感染迹象。该队列的年龄范围为22至78岁，75%为男性。迄今为止，疑似传播发生在住宅周围。
