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1
Indications for investigation of chronic gastrointestinal symptoms.慢性胃肠道症状的检查指征。
Arch Dis Child. 1995 Oct;73(4):354-5. doi: 10.1136/adc.73.4.354.
2
Use of serologic markers as a screening tool in inflammatory bowel disease compared with elevated erythrocyte sedimentation rate and anemia.与红细胞沉降率升高和贫血相比,血清学标志物在炎症性肠病中作为筛查工具的应用。
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3
[Inflammatory bowel disease in children and adolescents. When can the diagnosis be excluded without a referral to a pediatric gastroenterologist?].[儿童和青少年炎症性肠病。何时可不转诊至儿科胃肠病学家而排除诊断?]
Lakartidningen. 1999 Jan 6;96(1-2):49-51.
4
Role of endoscopy in inflammatory bowel disease.内镜检查在炎症性肠病中的作用。
Gastrointest Endosc Clin N Am. 2001 Oct;11(4):641-57, vi.
5
Laboratory values for children with newly diagnosed inflammatory bowel disease.新诊断炎症性肠病患儿的实验室检查值
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Faecal calprotectin as reliable non-invasive marker to assess the severity of mucosal inflammation in children with inflammatory bowel disease.粪便钙卫蛋白作为评估炎症性肠病患儿黏膜炎症严重程度的可靠非侵入性标志物。
Dig Liver Dis. 2008 Jul;40(7):547-53. doi: 10.1016/j.dld.2008.01.017. Epub 2008 Mar 20.
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Repeat endoscopy affects patient management in pediatric inflammatory bowel disease.重复内镜检查影响儿童炎症性肠病的患者管理。
Am J Gastroenterol. 2009 Mar;104(3):722-7. doi: 10.1038/ajg.2008.111. Epub 2009 Feb 10.
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[Consensus inflammatory intestinal diseases in children: ulcerative colitis and Crohn disease. Work Group Academic Medical Center, Amsterdam].[儿童共识性炎症性肠病:溃疡性结肠炎和克罗恩病。阿姆斯特丹学术医疗中心工作组]
Ned Tijdschr Geneeskd. 1996 Mar 9;140(10):544-50.
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Serum prohepcidin levels in chronic inflammatory bowel diseases.慢性炎症性肠病患者血清铁调素水平。
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Pediatric inflammatory bowel disease.小儿炎症性肠病
World J Gastroenterol. 2006 May 28;12(20):3204-12. doi: 10.3748/wjg.v12.i20.3204.

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Assessing the correlation between fecal calprotectin, blood markers and disease activity in pediatric inflammatory bowel disease.评估儿童炎症性肠病中粪便钙卫蛋白、血液标志物与疾病活动度之间的相关性。
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Selected Cytokines and Metalloproteinases in Inflammatory Bowel Disease.炎症性肠病中的精选细胞因子和金属蛋白酶。
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Assessing Severity of Disease in Patients with Ulcerative Colitis.评估溃疡性结肠炎患者的疾病严重程度。
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Use of C-Reactive Protein and Ferritin Biomarkers in Daily Pediatric Practice.C 反应蛋白和铁蛋白生物标志物在儿科日常实践中的应用。
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Biomarkers Predictive of Response to Thiopurine Therapy in Inflammatory Bowel Disease.炎症性肠病中硫嘌呤治疗反应的预测生物标志物
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Use of Laboratory Markers in Addition to Symptoms for Diagnosis of Inflammatory Bowel Disease in Children: A Meta-analysis of Individual Patient Data.除症状外使用实验室标志物诊断儿童炎症性肠病:个体患者数据的荟萃分析
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Measurement of Fractional Exhaled Nitric Oxide as a Marker of Disease Activity in Inflammatory Bowel Disease.测定呼出一氧化氮分数作为炎症性肠病疾病活动的标志物
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Utility of surrogate markers for the prediction of relapses in inflammatory bowel diseases.替代标志物在预测炎症性肠病复发中的应用。
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9
Current application of proteomics in biomarker discovery for inflammatory bowel disease.蛋白质组学在炎症性肠病生物标志物发现中的当前应用。
World J Gastrointest Pathophysiol. 2016 Feb 15;7(1):27-37. doi: 10.4291/wjgp.v7.i1.27.
10
Manganese superoxide dismutase plays an important role in the inflammatory process and predicts disease severity and activity in patients with ulcerative colitis.锰超氧化物歧化酶在炎症过程中发挥重要作用,并可预测溃疡性结肠炎患者的疾病严重程度和活动度。
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本文引用的文献

1
Acute phase proteins in chronic inflammatory bowel disease in childhood.儿童慢性炎症性肠病中的急性期蛋白
J Pediatr Gastroenterol Nutr. 1982;1(2):193-200. doi: 10.1097/00005176-198201020-00007.
2
Platelet count: a simple measure of activity in Crohn's disease.血小板计数:克罗恩病活动度的一项简易指标。
Br Med J (Clin Res Ed). 1983 May 7;286(6376):1476. doi: 10.1136/bmj.286.6376.1476.
3
C-reactive protein as an aid in the differentiation of functional and inflammatory bowel disorders.
Clin Chim Acta. 1985 May 30;148(2):105-9. doi: 10.1016/0009-8981(85)90219-0.
4
Laboratory assessment of disease activity in childhood Crohn's disease and ulcerative colitis.儿童克罗恩病和溃疡性结肠炎疾病活动度的实验室评估
J Pediatr Gastroenterol Nutr. 1986 Jan;5(1):93-6. doi: 10.1097/00005176-198601000-00017.
5
Serum concentrations of tumour necrosis factor alpha in childhood chronic inflammatory bowel disease.儿童慢性炎症性肠病中肿瘤坏死因子α的血清浓度
Gut. 1991 Aug;32(8):913-7. doi: 10.1136/gut.32.8.913.

慢性胃肠道症状的检查指征。

Indications for investigation of chronic gastrointestinal symptoms.

作者信息

Beattie R M, Walker-Smith J A, Murch S H

机构信息

Academic Department of Paediatric Gastroenterology, St Bartholomew's Hospital, London.

出版信息

Arch Dis Child. 1995 Oct;73(4):354-5. doi: 10.1136/adc.73.4.354.

DOI:10.1136/adc.73.4.354
PMID:7492204
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1511324/
Abstract

Simple routine blood tests (full blood count, platelet count, erythrocyte sedimentation rate, C reactive protein, and serum albumin) may select children with chronic gastrointestinal symptoms who require endoscopic assessment and are thus an important aid in the prediction of endoscopic status. When all of the results are normal then chronic inflammatory bowel disease is an unlikely diagnosis.

摘要

简单的常规血液检查(全血细胞计数、血小板计数、红细胞沉降率、C反应蛋白和血清白蛋白)可以筛选出需要进行内镜评估的有慢性胃肠道症状的儿童,因此对预测内镜检查结果有重要帮助。当所有结果都正常时,慢性炎症性肠病不太可能被诊断。