Bjordal K, Freng A, Thorvik J, Kaasa S
Department of Medical Oncology and Radiotherapy, Norwegian Radium Hospital, Oslo, Norway.
Eur J Cancer B Oral Oncol. 1995 Jul;31B(4):235-41. doi: 10.1016/0964-1955(95)00010-f.
One to six years after treatment for head and neck cancer, 68 patients were asked to fill in a questionnaire at home with a subsequent examination at the out-patient clinic of the Ullevål University Hospital. 50 patients (74%) both answered the questionnaire (the EORTC QLQ-C30, a diagnosis specific questionnaire module, the GHQ-20, and two questions from a population survey) and presented for examination where the clinician rated side effects after treatment, and filled in the Karnofsky Performance Status and the Spitzer's Quality of Life index. No patients had relapse or second primary tumours at the time of examination but a variety of post-treatment side effects were recorded. The patients appeared to report lower quality of life including more post-treatment side effects compared with the clinician's assessments. The cost-benefit of the standard clinical follow-ups in terms of increased survival may be questioned. Patients seem to need better support in coping with the physical and psychosocial problems which often appear.
在接受头颈癌治疗后的一至六年，68名患者被要求在家中填写一份问卷，随后在乌勒瓦尔大学医院门诊接受检查。50名患者（74%）既回答了问卷（欧洲癌症研究与治疗组织核心问卷QLQ-C30、一个特定诊断问卷模块、一般健康问卷GHQ-20以及一份人口调查问卷中的两个问题），又前来接受检查，临床医生对治疗后的副作用进行评分，并填写卡氏功能状态量表和斯皮策生活质量指数。在检查时，没有患者出现复发或第二原发性肿瘤，但记录了各种治疗后的副作用。与临床医生的评估相比，患者报告的生活质量似乎较低，包括更多的治疗后副作用。标准临床随访在提高生存率方面的成本效益可能受到质疑。患者似乎需要在应对经常出现的身体和心理社会问题方面得到更好的支持。
