Bjordal K, Ahlner-Elmqvist M, Tollesson E, Jensen A B, Razavi D, Maher E J, Kaasa S
Dept. of Medical Oncology and Radiotherapy, Norweigan Radium Hospital, Oslo.
Acta Oncol. 1994;33(8):879-85. doi: 10.3109/02841869409098450.
A head and neck cancer specific questionnaire module designed to be used in quality of life assessments before, during, and after radiotherapy and surgery, with or without combinations with chemotherapy has been developed in accordance with guidelines given by the EORTC Quality of Life Study Group. Relevant issues were generated by means of literature search, and interviews with specialists and patients. Pre-testing of a preliminary questionnaire module was performed in patients from Norway, Sweden, Denmark, United Kingdom and French-speaking Belgium. The resulting head and neck cancer module, the EORTC QLQ-H&N37, includes 37 items concerning disease and treatment related symptoms, social function and sexuality. By using a combination of the general EORTC QLQ-C30 and the EORTC QLQ-H&N37, health-related quality of life measurements may be compared between studies in different cancer populations, and still be sensitive to changes in the target population.
根据欧洲癌症研究与治疗组织（EORTC）生活质量研究小组给出的指南，已经开发出了一个专门用于头颈癌的问卷模块，该模块可用于放疗和手术前、手术中和手术后的生活质量评估，无论是否联合化疗。通过文献检索、与专家和患者访谈等方式确定了相关问题。在来自挪威、瑞典、丹麦、英国和说法语的比利时的患者中，对初步问卷模块进行了预测试。最终形成的头颈癌模块即EORTC QLQ-H&N37，包含37个有关疾病和治疗相关症状、社会功能及性功能的条目。通过联合使用EORTC通用的QLQ-C30和EORTC QLQ-H&N37，不同癌症人群研究之间的健康相关生活质量测量结果可以进行比较，并且对目标人群的变化仍保持敏感。
