基于重组风疹样颗粒的新型酶免疫测定法Cobas Core风疹IgG EIA的评估。
Evaluation of Cobas Core Rubella IgG EIA recomb, a new enzyme immunoassay based on recombinant rubella-like particles.
作者信息
Grangeot-Keros L, Pustowoit B, Hobman T
机构信息
Department of Microbiology and Immunology, Hôpital Antoine Béclère, Clamart, France.
出版信息
J Clin Microbiol. 1995 Sep;33(9):2392-4. doi: 10.1128/jcm.33.9.2392-2394.1995.
Abstract
Cobas Core Rubella IgG EIA recomb (Roche), a new, commercially available rubella enzyme immunoassay using recombinant rubella-like particles, was compared with a hemagglutination inhibition assay (Rubenosticon; Organon Teknika) and two whole-virus enzyme immunoassays (IMx [Abbott] and Platelia [Sanofi Diagnostics Pasteur]). Compared with those of these reference assays, the relative sensitivities of Cobas Core Rubella IgG recomb were 100, 94, and 95.9%, with specificities amounting to 80.8, 98, and 98.2%, respectively.
摘要
Cobas Core风疹IgG重组酶免疫测定法（罗氏公司）是一种新型的、可商购的使用重组风疹样颗粒的风疹酶免疫测定法，将其与血凝抑制试验（Rubenosticon；欧加农公司）以及两种全病毒酶免疫测定法（IMx [雅培公司]和Platelia [赛诺菲诊断公司巴斯德分部]）进行了比较。与这些参比测定法相比，Cobas Core风疹IgG重组酶免疫测定法的相对灵敏度分别为100%、94%和95.9%，特异性分别为80.8%、98%和98.2%。
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