Schaefer L E, Dyke J W, Meglio F D, Murray P R, Crafts W, Niles A C
Diagnostics Division, Abbott Laboratories, Abbott Park, Illinois 60064.
J Clin Microbiol. 1989 Nov;27(11):2410-3. doi: 10.1128/jcm.27.11.2410-2413.1989.
The ability of the Abbott IMx automated analyzer to detect immunoglobulin G (IgG) and IgM antibodies to rubella virus and to Toxoplasma gondii was compared with the abilities of RUBAZYME, RUBAZYME-M, ABBOTT TOXO-G enzyme immunoassay, and ABBOTT TOXO-M enzyme immunoassay, respectively. Specimens that produced discordant results were evaluated by RUBACELL II, Behring Enzygnost-Rubella enzyme-linked immunosorbent assay, Behring Enzygnost Toxoplasmosis/IgG, and bioMerieux Toxo-ISAGA (immunosorbent agglutination assay), respectively. After resolution of discordant results, IMx Rubella IgG, IMx Rubella IgM, IMx Toxo IgG, and IMx Toxo IgM antibody assays had sensitivities of 99.9, 100, 98.0, and 100%; specificities of 98.9, 99.0, 97.5, and 98.7%; and accuracies of 99.8, 99.3, 97.8, and 98.8%, respectively.
将雅培IMx自动分析仪检测风疹病毒和弓形虫免疫球蛋白G（IgG）及IgM抗体的能力，分别与RUBAZYME、RUBAZYME - M、雅培弓形虫酶免疫测定法及雅培弓形虫M酶免疫测定法的能力进行了比较。对产生不一致结果的标本，分别采用RUBACELL II、贝林风疹酶联免疫吸附测定法、贝林弓形虫病/IgG及生物梅里埃弓形虫免疫吸附凝集测定法进行评估。在解决不一致结果后，IMx风疹IgG、IMx风疹IgM、IMx弓形虫IgG及IMx弓形虫IgM抗体检测的灵敏度分别为99.9%、100%、98.0%和100%；特异性分别为98.9%、99.0%、97.5%和98.7%；准确度分别为99.8%、99.3%。97.8%和98.8%。
