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J Clin Microbiol. 1995 Sep;33(9):2483-4. doi: 10.1128/jcm.33.9.2483-2484.1995.
2
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Noninvasive screening for genital chlamydial infections in asymptomatic men: Strategies and costs using a urine PCR assay.无症状男性生殖器衣原体感染的非侵入性筛查：使用尿液PCR检测的策略与成本
Can J Infect Dis. 1998 Sep;9(5):281-6. doi: 10.1155/1998/286027.
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Impact of reference standard sensitivity on accuracy of rapid antigen detection assays and a leukocyte esterase dipstick for diagnosis of Chlamydia trachomatis infection in first-void urine specimens from men.参考标准敏感性对快速抗原检测试验及白细胞酯酶试纸条检测男性首次晨尿标本中沙眼衣原体感染准确性的影响
J Clin Microbiol. 1999 Sep;37(9):2777-80. doi: 10.1128/JCM.37.9.2777-2780.1999.
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Comparison of performances of two commercially available tests, a PCR assay and a ligase chain reaction test, in detection of urogenital Chlamydia trachomatis infection.两种市售检测方法（一种聚合酶链反应检测和一种连接酶链反应检测）在检测泌尿生殖系统沙眼衣原体感染方面的性能比较。
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False-negative results of a ligase chain reaction assay to detect Chlamydia trachomatis due to inhibitors in urine.由于尿液中的抑制剂导致连接酶链反应检测沙眼衣原体出现假阴性结果。
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本文引用的文献

1
Screening urine with a leukocyte esterase strip and subsequent chlamydial testing of asymptomatic men attending primary care practitioners.使用白细胞酯酶试纸筛查尿液，并对到初级保健医生处就诊的无症状男性进行后续衣原体检测。
Sex Transm Dis. 1993 May-Jun;20(3):152-7. doi: 10.1097/00007435-199305000-00007.
2
Amplification of Chlamydia trachomatis DNA by ligase chain reaction.通过连接酶链反应扩增沙眼衣原体DNA。
J Clin Microbiol. 1993 Mar;31(3):729-31. doi: 10.1128/jcm.31.3.729-731.1993.
3
An economic evaluation of screening for Chlamydia trachomatis in adolescent males.对青少年男性沙眼衣原体筛查的经济学评估。
JAMA. 1993 Nov 3;270(17):2057-64. doi: 10.1001/jama.1993.03510170047029.
4
Detection of Chlamydia trachomatis in the urine of young Norwegian males by enzyme immunoassay.采用酶免疫测定法检测挪威年轻男性尿液中的沙眼衣原体。
Eur J Clin Microbiol Infect Dis. 1993 Oct;12(10):746-9. doi: 10.1007/BF02098461.
5
Long-term eradication of Chlamydia trachomatis genital infection after antimicrobial therapy. Evidence against persistent infection.抗菌治疗后沙眼衣原体生殖器感染的长期根除。反对持续性感染的证据。
JAMA. 1993 Nov 3;270(17):2071-5.
6
Diagnosis of Chlamydia trachomatis infections in men and women by testing first-void urine by ligase chain reaction.通过连接酶链反应检测首次晨尿诊断男性和女性沙眼衣原体感染
J Clin Microbiol. 1994 Nov;32(11):2682-5. doi: 10.1128/jcm.32.11.2682-2685.1994.
7
Ligase chain reaction to detect Chlamydia trachomatis infection of the cervix.连接酶链反应检测宫颈沙眼衣原体感染
J Clin Microbiol. 1994 Oct;32(10):2540-3. doi: 10.1128/jcm.32.10.2540-2543.1994.
8
Prevalence of cervical Chlamydia trachomatis and Neisseria gonorrhoeae in female adolescents.女性青少年宫颈沙眼衣原体和淋病奈瑟菌的患病率
Pediatrics. 1983 Mar;71(3):333-6.
9
Prevalence of urethral Chlamydia trachomatis and Neisseria gonorrhoeae among asymptomatic, sexually active adolescent boys.无症状性活跃青春期男孩中尿道沙眼衣原体和淋病奈瑟菌的患病率
J Infect Dis. 1987 Jul;156(1):223-4. doi: 10.1093/infdis/156.1.223.
10
Urinary leukocyte esterase screening test for asymptomatic chlamydial and gonococcal infections in males.男性无症状衣原体和淋病奈瑟菌感染的尿液白细胞酯酶筛查试验
JAMA. 1989 Nov 10;262(18):2562-6.

通过白细胞酯酶试验和连接酶链反应对无症状男性衣原体感染进行尿液样本筛查。

Screening urine samples by leukocyte esterase test and ligase chain reaction for chlamydial infections among asymptomatic men.

作者信息

Anestad G, Berdal B P, Scheel O, Mundal R, Odinsen O, Skaug K, Khalil O S, Plier P, Lee H

机构信息

Department of Virology, National Institute of Public Health, Oslo, Norway.

出版信息

J Clin Microbiol. 1995 Sep;33(9):2483-4. doi: 10.1128/jcm.33.9.2483-2484.1995.

DOI:10.1128/jcm.33.9.2483-2484.1995
PMID:7494054
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC228448/
Abstract

Urine samples from 358 asymptomatic males were screened for urethral inflammation by the leukocyte esterase (LE) test and for Chlamydia trachomatis by the ligase chain reaction (LCR). LE and LCR positivity rates were 7.5% (27 of 358 samples) and 2.8% (10 of 358 samples), respectively. Eight of the 10 LCR-positive samples were detected by the LE screening test. The urine LE prescreening test in combination with the LCR assay may be a reasonable approach for genitourinary chlamydial disease control.

摘要

通过白细胞酯酶（LE）试验对358名无症状男性的尿液样本进行尿道炎症筛查，并通过连接酶链反应（LCR）检测沙眼衣原体。LE和LCR阳性率分别为7.5%（358份样本中的27份）和2.8%（358份样本中的10份）。10份LCR阳性样本中有8份通过LE筛查试验检测到。尿液LE预筛查试验与LCR检测相结合可能是控制泌尿生殖道衣原体疾病的合理方法。