Lima E G, Spritzer N, Herkenhoff F L, Bermudes A, Vasquez E C
Department of Physiological Sciences, UFES, Vitoria, Brazil.
Hypertension. 1995 Dec;26(6 Pt 2):1121-4. doi: 10.1161/01.hyp.26.6.1121.
Few studies have investigated the significance of abnormal increases in systolic pressure during exercise in patients with high normal blood pressure and its correlation with 24-hour ambulatory blood pressure monitoring and left ventricular structure. This study was performed in 30 sedentary subjects (42 +/- 4 years old) with high normal blood pressure. Fifteen subjects presenting < 220 mm Hg systolic pressure during ergometric exercise were compared with 15 others with systolic pressure > or = 220 mm Hg. Average 24-hour (systolic, 127 +/- 5 versus 142 +/- 4 mm Hg, P < .01; diastolic, 82 +/- 4 versus 92 +/- 3 mm Hg, P < .01), daytime (systolic, 130 +/- 6 versus 144 +/- 4 mm Hg, P < .01; diastolic, 84 +/- 4 versus 92 +/- 4 mm Hg, P < .01), and nighttime (systolic, 116 +/- 7 versus 132 +/- 6 mm Hg, P < .01; diastolic, 72 +/- 6 versus 85 +/- 6 mm Hg, P < .01) ambulatory blood pressure monitoring values were significantly higher in subjects with an exaggerated blood pressure response to exercise. No significant differences were observed in left ventricular morphology. These findings indicate that subjects presenting high normal blood pressure and exaggerated systolic pressure during exercise show significantly high ambulatory blood pressure monitoring values that are not associated with left ventricular hypertrophy.
很少有研究调查血压正常高值患者运动期间收缩压异常升高的意义及其与24小时动态血压监测和左心室结构的相关性。本研究纳入了30名久坐不动的血压正常高值受试者（42±4岁）。将运动试验期间收缩压<220 mmHg的15名受试者与收缩压≥220 mmHg的另外15名受试者进行比较。运动时血压反应过度的受试者24小时平均（收缩压，127±5对142±4 mmHg，P<.01；舒张压，82±4对92±3 mmHg，P<.01）、日间（收缩压，130±6对144±4 mmHg，P<.01；舒张压，84±4对92±4 mmHg，P<.01）和夜间（收缩压，116±7对132±6 mmHg，P<.01；舒张压，72±6对85±6 mmHg，P<.01）动态血压监测值显著更高。左心室形态未观察到显著差异。这些发现表明，血压正常高值且运动期间收缩压过度升高的受试者动态血压监测值显著升高，且与左心室肥厚无关。
