由簇BoWC8（TC23）单克隆抗体所定义的一种晚期激活抗原的特性分析
Characterization of a late activation antigen defined by monoclonal antibodies of cluster BoWC8 (TC23).
作者信息
Nthale J M, Naessens J
机构信息
International Laboratory for Research on Animal Diseases, Nairobi, Kenya.
出版信息
Vet Immunol Immunopathol. 1993 Nov;39(1-3):201-8. doi: 10.1016/0165-2427(93)90182-4.
PMID:7508656
Abstract
Three monoclonal antibodies (mAbs), P13 (#90), IL-A78 (#76) and IL-A79 (#77), defined a new cluster, called BoWC8. The antigen defined by these mAbs is a molecule of 160 kDa under reducing conditions, and is expressed on lymphocytes late (6 days) after activation. The molecule can be expressed on multiplying T cells, but not on B cells.
摘要
三种单克隆抗体（mAb），即P13（编号90）、IL-A78（编号76）和IL-A79（编号77），定义了一个新的细胞簇，称为BoWC8。这些单克隆抗体所定义的抗原在还原条件下是一种160 kDa的分子，在激活后较晚时间（6天）在淋巴细胞上表达。该分子可在增殖的T细胞上表达，但不在B细胞上表达。
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