Schreiter-Gasser U, Gasser T, Ziegler P
Zentralinstitut für Seelische Gesundheit, Mannheim, Germany.
Electroencephalogr Clin Neurophysiol. 1994 Apr;90(4):267-72. doi: 10.1016/0013-4694(94)90144-9.
We report EEG findings in 15 presenile Alzheimer patients (probable Alzheimer's disease according to NINCDS-ADRDA criteria) in relation to clinical characteristics. The quantitative EEG was analysed in terms of absolute band power while accounting for EOG and EMG artifacts, respectively. The degree of dementia is strongly reflected by an increase of power in the delta frequency band, accentuated on the left hemisphere, as well as decrease of alpha activity. Longer duration of disease is associated with a decrease of power in the alpha frequency band, earlier age at onset with an additional increase of power in the theta frequency band. Visual EEG evaluation correlates highly with the degree of dementia, in contrast to visually assessed CCT.
我们报告了15例早老性阿尔茨海默病患者（根据NINCDS-ADRDA标准确诊为可能的阿尔茨海默病）的脑电图（EEG）结果及其临床特征。分别在考虑眼电图（EOG）和肌电图（EMG）伪迹的情况下，对定量脑电图的绝对频段功率进行了分析。痴呆程度在δ频段功率增加中得到强烈反映，以左半球更为明显，同时α活动减少。病程较长与α频段功率降低相关，发病年龄较早则与θ频段功率额外增加相关。与视觉评估的计算机断层扫描（CCT）不同，视觉脑电图评估与痴呆程度高度相关。
