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本文引用的文献

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Typing of hepatitis C virus isolates and characterization of new subtypes using a line probe assay.使用线性探针分析对丙型肝炎病毒分离株进行分型及新亚型的特征分析。
J Gen Virol. 1993 Jun;74 ( Pt 6):1093-102. doi: 10.1099/0022-1317-74-6-1093.
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Hepatitis C virus genotypes: an investigation of type-specific differences in geographic origin and disease.丙型肝炎病毒基因型：关于地理起源和疾病中类型特异性差异的调查。
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Identification of genotypes of hepatitis C virus by sequence comparisons in the core, E1 and NS-5 regions.通过对核心区、E1区和NS-5区进行序列比较来鉴定丙型肝炎病毒的基因型。
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A proposed system for the nomenclature of hepatitis C viral genotypes.丙型肝炎病毒基因型命名的拟议系统。
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Prevalence of hepatitis C virus genotypes in Italy.意大利丙型肝炎病毒基因型的流行情况。
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Geographical distribution of hepatitis C virus genotypes in blood donors: an international collaborative survey.献血者中丙型肝炎病毒基因型的地理分布：一项国际合作调查。
J Clin Microbiol. 1994 Apr;32(4):884-92. doi: 10.1128/jcm.32.4.884-892.1994.
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Mapping of serotype-specific, immunodominant epitopes in the NS-4 region of hepatitis C virus (HCV): use of type-specific peptides to serologically differentiate infections with HCV types 1, 2, and 3.丙型肝炎病毒（HCV）NS-4区域血清型特异性免疫显性表位的定位：利用型特异性肽对HCV 1、2和3型感染进行血清学鉴别
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Analysis of hepatitis C virus genotypes by a line probe assay and correlation with antibody profiles.通过线性探针分析丙型肝炎病毒基因型及其与抗体谱的相关性。
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Classification of hepatitis C viruses based on phylogenetic analysis of the envelope 1 and nonstructural 5B regions and identification of five additional subtypes.基于包膜1区和非结构5B区系统发育分析的丙型肝炎病毒分类及另外五种亚型的鉴定。
Proc Natl Acad Sci U S A. 1994 Oct 11;91(21):10134-8. doi: 10.1073/pnas.91.21.10134.
10
Significance of highly positive c22-3 "indeterminate" second-generation hepatitis C virus (HCV) recombinant immunoblot assay (RIBA) and resolution by third-generation HCV RIBA.第二代丙型肝炎病毒（HCV）重组免疫印迹法（RIBA）检测结果高度阳性的“不确定”结果的意义及通过第三代HCV RIBA进行的结果解析
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丙型肝炎病毒（HCV）基因型对HCV重组免疫印迹分析模式的影响。

Influence of hepatitis C virus (HCV) genotypes on HCV recombinant immunoblot assay patterns.

作者信息

Pawlotsky J M, Roudot-Thoraval F, Pellet C, Aumont P, Darthuy F, Remire J, Duval J, Dhumeaux D

机构信息

Department of Bacteriology and Virology, Hôpital Henri Mondor, Université Paris XII, Créteil, France.

出版信息

J Clin Microbiol. 1995 May;33(5):1357-9. doi: 10.1128/jcm.33.5.1357-1359.1995.

DOI:10.1128/jcm.33.5.1357-1359.1995
PMID:7542272
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC228164/
Abstract

Ninety-six patients with chronic hepatitis C were studied. A second-generation recombinant immunoblot assay detected anti-NS4 antibodies significantly more often in patients infected by hepatitis C virus genotype 1 than in patients infected by other types. By a third-generation recombinant immunoblot assay, the prevalences of the four antibodies measured did not differ according to the hepatitis C virus genotype.

摘要

对96例慢性丙型肝炎患者进行了研究。第二代重组免疫印迹法检测发现，丙型肝炎病毒1型感染者中抗NS4抗体的检出率显著高于其他类型感染者。通过第三代重组免疫印迹法检测，所测的四种抗体的患病率在不同丙型肝炎病毒基因型患者中并无差异。