丙型肝炎病毒（HCV）基因型对HCV重组免疫印迹分析模式的影响。
Influence of hepatitis C virus (HCV) genotypes on HCV recombinant immunoblot assay patterns.
作者信息
Pawlotsky J M, Roudot-Thoraval F, Pellet C, Aumont P, Darthuy F, Remire J, Duval J, Dhumeaux D
机构信息
Department of Bacteriology and Virology, Hôpital Henri Mondor, Université Paris XII, Créteil, France.
出版信息
J Clin Microbiol. 1995 May;33(5):1357-9. doi: 10.1128/jcm.33.5.1357-1359.1995.
Abstract
Ninety-six patients with chronic hepatitis C were studied. A second-generation recombinant immunoblot assay detected anti-NS4 antibodies significantly more often in patients infected by hepatitis C virus genotype 1 than in patients infected by other types. By a third-generation recombinant immunoblot assay, the prevalences of the four antibodies measured did not differ according to the hepatitis C virus genotype.
摘要
对96例慢性丙型肝炎患者进行了研究。第二代重组免疫印迹法检测发现，丙型肝炎病毒1型感染者中抗NS4抗体的检出率显著高于其他类型感染者。通过第三代重组免疫印迹法检测，所测的四种抗体的患病率在不同丙型肝炎病毒基因型患者中并无差异。
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