Mutti A, Cavatorta A, Borghi A, Pedroni C, Franchini I, Borghetti A
Ann Ist Super Sanita. 1978;14(3):619-24.
Biological and environmental monitoring of chromium exposure was carried out on 20 welders working with special electrodes in the manufacture of tank-cars. The workers were divided in groups, according to the different degree of chromium accumulation, which was determined by renal clearance of diffusible chromium. A closed linear relationship between TWA concentration of hydrosoluble chromium in air and urinary excretion of the metal at the end of exposure was observed. The parameters of regression lines in welders with more (clearance 10 ml/min) or less (clearance 5 ml/min) accumulation of chromium suggest that the renal burden influences not only the basal excretion, but also the excretion at the end of exposure. We underline the difficulty in the determination of correct biological limits if we take them from TLV in air. We must at least consider the degree of accumulation in exposed workers too.
对20名在罐车制造中使用特殊电极的焊工进行了铬暴露的生物和环境监测。根据铬蓄积程度的不同将工人分组，铬蓄积程度由可扩散铬的肾清除率确定。观察到空气中水溶性铬的时间加权平均浓度与暴露结束时金属的尿排泄量之间存在封闭的线性关系。铬蓄积较多（清除率10 ml/min）或较少（清除率5 ml/min）的焊工的回归线参数表明，肾脏负担不仅影响基础排泄，还影响暴露结束时的排泄。我们强调，如果从空气中的阈限值来确定正确的生物限值会有困难。我们至少还必须考虑暴露工人的蓄积程度。
