Giles D R, Wagener J S, Accurso F J, Butler-Simon N
Department of Respiratory Therapy, Children's Hospital, University of Colorado School of Medicine, Denver, USA.
Chest. 1995 Oct;108(4):952-4. doi: 10.1378/chest.108.4.952.
To compare the short-term effects of postural drainage with clapping (PD) and autogenic drainage (AD) on oxygen saturation, pulmonary function, and sputum recovery, we studied ten patients with cystic fibrosis (CF) randomly treated with PD or AD on separate days. Pulse oximetry was monitored and sputum was collected during and for 1 h following each treatment. Pulmonary function was measured before and then 1, 15, and 60 min after each treatment. There was no significant difference in the amount of sputum recovered with AD (14.0 +/- 3.5 g) vs PD (10.4 +/- 3.0 g) and no significant differences in pulmonary function occurred. Oxygen saturation during PD fell from 93.3 +/- 0.7% to 91.2 +/- 0.8% (p < 0.01) and required 15 min following treatment to return to baseline. Oxygen saturation did not fall during AD and increased to 94.5 +/- 0.7% by 1 h following treatment (baseline, 93.3 +/- 0.8%; p < 0.01). We conclude that AD is less likely to produce oxygen desaturation and may be better tolerated by patients with CF, while producing similar benefits in sputum clearance.
为比较体位引流配合拍背（PD）和自主引流（AD）对氧饱和度、肺功能及痰液排出的短期影响，我们对10例囊性纤维化（CF）患者进行了研究，他们在不同日期分别接受PD或AD治疗。每次治疗期间及治疗后1小时监测脉搏血氧饱和度并收集痰液。在每次治疗前以及治疗后1、15和60分钟测量肺功能。AD组咳出的痰液量（14.0±3.5克）与PD组（10.4±3.0克）相比无显著差异，肺功能也无显著差异。PD治疗期间氧饱和度从93.3±0.7%降至91.2±0.8%（p<0.01），治疗后需15分钟恢复至基线水平。AD治疗期间氧饱和度未下降，治疗后1小时升至94.5±0.7%（基线为93.3±0.8%；p<0.01）。我们得出结论，AD导致氧饱和度下降的可能性较小，CF患者可能对其耐受性更好，同时在痰液清除方面产生类似的效果。
