血友病患者、献血者和肝炎患者中的戊型肝炎病毒抗体。

Hepatitis E virus antibodies among patients with hemophilia, blood donors, and hepatitis patients.

作者信息

Zaaijer H L, Mauser-Bunschoten E P, ten Veen J H, Kapprell H P, Kok M, van den Berg H M, Lelie P N

机构信息

Central Laboratory of The Netherlands Red Cross Blood Transfusion Service, Amsterdam.

出版信息

J Med Virol. 1995 Jul;46(3):244-6. doi: 10.1002/jmv.1890460313.

DOI:10.1002/jmv.1890460313

PMID:7561797

Abstract

The presence of antibodies to hepatitis E virus (HEV) was studied among hemophiliacs, blood donors, and hepatitis patients. Four of 296 (1.4%) hemophiliacs and 5 of 1,275 (0.4%) donors were confirmed as positive for HEV antibodies (difference was not significant: P = 0.07). Parenteral transmission of HEV to hemophiliacs was thus rare or nonexistent. Seven of 187 hepatitis patients were found with HEV antibodies (IgG and IgM). Six persons fell ill shortly after arriving from HEV-endemic countries. The seventh patient, without a history of travel, represents a case of nontropical hepatitis E. Consequently, hepatitis E should be considered in patients suffering from acute non-ABC hepatitis, even in industrialized countries.

摘要

在血友病患者、献血者和肝炎患者中研究了戊型肝炎病毒（HEV）抗体的存在情况。296名血友病患者中有4名（1.4%），1275名献血者中有5名（0.4%）被确认为HEV抗体阳性（差异不显著：P = 0.07）。因此，HEV经肠道外传播给血友病患者的情况很少见或不存在。187名肝炎患者中有7名检测到HEV抗体（IgG和IgM）。6人从HEV流行国家抵达后不久发病。第七名患者没有旅行史，代表了一例非热带戊型肝炎病例。因此，即使在工业化国家，患有急性非ABC型肝炎的患者也应考虑戊型肝炎。