对艾滋病患者中穿透支原体临床分离株进行的体外抗生素敏感性测试。
In vitro antibiotic susceptibility testing of clinical isolates of Mycoplasma penetrans from patients with AIDS.
作者信息
Hayes M M, Foo H H, Timenetsky J, Lo S C
机构信息
Department of Infectious and Parasitic Disease Pathology, Armed Forces Institute of Pathology, Washington, D.C. 20306-6000, USA.
出版信息
Antimicrob Agents Chemother. 1995 Jun;39(6):1386-7. doi: 10.1128/AAC.39.6.1386.
Abstract
In vitro susceptibilities of Mycoplasma penetrans were determined. MICs and MBCs were determined. The MICs at which 50% of the isolates are inhibited (micrograms per milliliter) for broth dilution testing were as follows: azithromycin, 0.039; chloramphenicol, 0.625; ciprofloxacin, 0.156; clindamycin, 0.078; doxycycline, 0.312; erythromycin, 0.312; gentamicin. > 10; levofloxacin, 0.078; lincomycin, 0.625; streptomycin, > 10; and tetracycline, 1.25. Bactericidal activity was significant only for ciprofloxacin (MBC at which 50% of the isolates are killed, 0.312 microgram/ml) and levofloxacin (MBC at which 50% of the isolates are killed, 0.312 microgram/ml).
摘要
测定了穿透支原体的体外药敏情况。测定了最低抑菌浓度（MIC）和最低杀菌浓度（MBC）。肉汤稀释试验中使50%分离株受到抑制的MIC（微克/毫升）如下：阿奇霉素，0.039；氯霉素，0.625；环丙沙星，0.156；克林霉素，0.078；多西环素，0.312；红霉素，0.312；庆大霉素，>10；左氧氟沙星，0.078；林可霉素，0.625；链霉素，>10；四环素，1.25。仅环丙沙星（使50%分离株被杀灭的MBC，0.312微克/毫升）和左氧氟沙星（使50%分离株被杀灭的MBC，0.312微克/毫升）具有显著杀菌活性。
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