淋巴系统的进化。II. 所有虹鳟淋巴细胞上免疫球蛋白决定簇的证据及混合白细胞反应的证明。

Evolution of the lymphoid system. II. Evidence for immunoglobulin determinants on all rainbow trout lymphocytes and demonstration of mixed leukocyte reaction.

作者信息

Etlinger H M, Hodgins H O, Chiller J M

出版信息

Eur J Immunol. 1977 Dec;7(12):881-7. doi: 10.1002/eji.1830071212.

DOI:10.1002/eji.1830071212

PMID:75803

Abstract

Indirect fluorescent antibody analyses utilizing antiserum specific for rainbow trout serum immunoglobulin (Ig) demonstrated that essentially all rainbow trout lymphocytes from thymus, spleen, anterior kidney and peripheral blood possess either Ig determinants or structures which cross-react with those determinants found on serum Ig. Peripheral blood leukocytes from rainbow trout were found to be caple of participating in a mixed leukocyte reaction. This observation is discussed in terms of the evolution of T cell function.

摘要

利用针对虹鳟血清免疫球蛋白（Ig）的抗血清进行的间接荧光抗体分析表明，基本上所有来自胸腺、脾脏、前肾和外周血的虹鳟淋巴细胞都具有Ig决定簇或与血清Ig上发现的那些决定簇发生交叉反应的结构。已发现虹鳟的外周血白细胞能够参与混合白细胞反应。根据T细胞功能的进化对这一观察结果进行了讨论。

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