MMWR Morb Mortal Wkly Rep. 1995 Jul 14;44(27):501-3.
During February-March, 1994, four persons in Helena, Montana (1995 population: 24,569), developed bloody diarrhea and severe abdominal cramps. Stool cultures for Salmonella, Shigella, Campylobacter, and Escherichia coli O157:H7 were negative; however, sorbitol-negative E. coli colonies were identified in stools from all four patients. Isolates from three patients were identified at CDC as a rare serotype--E. coli O104:H21 that produced Shiga-like toxin II. This report summarizes the epidemiologic and laboratory investigations of this outbreak by the Lewis and Clark County Department of Health and Environmental Sciences, the Montana Department of Health and Environmental Sciences (MDHES), and CDC.
1994年2月至3月期间，蒙大拿州海伦娜市（1995年人口：24,569）有4人出现血性腹泻和严重腹痛。沙门氏菌、志贺氏菌、弯曲杆菌和大肠杆菌O157:H7的粪便培养结果均为阴性；然而，在所有4名患者的粪便中均鉴定出了山梨醇阴性的大肠杆菌菌落。疾病控制与预防中心（CDC）鉴定出3名患者的分离株为一种罕见血清型——产志贺样毒素II的大肠杆菌O104:H21。本报告总结了刘易斯和克拉克县卫生与环境科学部、蒙大拿州卫生与环境科学部（MDHES）以及疾病控制与预防中心（CDC）对此次疫情的流行病学和实验室调查情况。
