Bobek P, Hromadová M, Ozdín L
Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava.
Experientia. 1995 Jun 14;51(6):589-91. doi: 10.1007/BF02128749.
The effect of dried oyster mushroom (Pleurotus ostreatus) on cholesterol (C) content in serum, in lipoproteins and in liver, and on the activity of 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase in liver microsomes, was studied in male rats (strain Wistar, initial body weight 75 g) fed on low-cholesterol (9 mg/100 g) and high-cholesterol (0.3%) diets. Addition of 5% oyster mushroom to both diets reduced significantly the C-content in serum (by 30%), in very-low- and low-density lipoproteins (in a 1:1 ratio to the decrease of total serum C) and in liver (by 50%), as well as the activity of HMG-CoA reductase (by more than 30%).
在以低胆固醇（9毫克/100克）和高胆固醇（0.3%）饮食喂养的雄性大鼠（Wistar品系，初始体重75克）中，研究了干平菇（糙皮侧耳）对血清、脂蛋白和肝脏中胆固醇（C）含量以及肝脏微粒体中3-羟基-3-甲基戊二酰辅酶A（HMG-CoA）还原酶活性的影响。在两种饮食中添加5%的平菇均显著降低了血清中C含量（降低30%）、极低密度和低密度脂蛋白中的C含量（与血清总C含量降低比例为1:1）以及肝脏中的C含量（降低50%），同时也降低了HMG-CoA还原酶的活性（降低超过30%）。
