围产期接触二噁英类化合物研讨会。I. 总结。
Workshop on perinatal exposure to dioxin-like compounds. I. Summary.
作者信息
Lindström G, Hooper K, Petreas M, Stephens R, Gilman A
机构信息
Hazardous Materials Laboratory, Cal EPA, Berkeley 94704, USA.
出版信息
Environ Health Perspect. 1995 Mar;103 Suppl 2(Suppl 2):135-42. doi: 10.1289/ehp.103-1518837.
Abstract
An international workshop reviewed 20 ongoing or recently completed studies of the effects of perinatal exposures to dioxins, dibenzofurans, and PCBs on the reproductive, endocrine, neurodevelopmental, and immune systems. Many of the observed effects are consistent with these compounds acting as "environmental hormones" or endocrine disrupters. This report summarizes the conclusions and future directions described at the workshop.
摘要
一个国际研讨会对20项正在进行或最近完成的关于围产期接触二噁英、二苯并呋喃和多氯联苯对生殖、内分泌、神经发育和免疫系统影响的研究进行了评审。观察到的许多影响与这些化合物作为“环境激素”或内分泌干扰物的作用一致。本报告总结了研讨会上所述的结论和未来方向。
相似文献
1
Workshop on perinatal exposure to dioxin-like compounds. I. Summary.围产期接触二噁英类化合物研讨会。I. 总结。
Environ Health Perspect. 1995 Mar;103 Suppl 2(Suppl 2):135-42. doi: 10.1289/ehp.103-1518837.
2
Workshop on perinatal exposure to dioxin-like compounds. V. Immunologic effects.围产期接触二噁英类化合物研讨会。五、免疫效应。
Environ Health Perspect. 1995 Mar;103 Suppl 2(Suppl 2):157-60. doi: 10.1289/ehp.95103s2157.
3
Workshop on perinatal exposure to dioxin-like compounds. II. Reproductive effects.围产期接触二噁英类化合物研讨会。II. 生殖影响。
Environ Health Perspect. 1995 Mar;103 Suppl 2(Suppl 2):143-5. doi: 10.1289/ehp.95103s2143.
4
Workshop on perinatal exposure to dioxin-like compounds. VI. Role of biomarkers.围产期接触二噁英类化合物研讨会。VI.生物标志物的作用。
Environ Health Perspect. 1995 Mar;103 Suppl 2(Suppl 2):161-7. doi: 10.1289/ehp.95103s2161.
5
Workshop on perinatal exposure to dioxin-like compounds. III. Endocrine effects.围产期接触二噁英类化合物研讨会。III. 内分泌影响。
Environ Health Perspect. 1995 Mar;103 Suppl 2(Suppl 2):147-50. doi: 10.1289/ehp.95103s2147.
6
Neurodevelopmental, immunological and endocrinological indices of perinatal human exposure to PCBs and dioxins.围产期人类接触多氯联苯和二恶英的神经发育、免疫和内分泌指标。
Chemosphere. 1998 Oct-Nov;37(9-12):1845-53. doi: 10.1016/s0045-6535(98)00250-1.
7
Polychlorinated biphenyls, polychlorinated dibenzo-p-dioxins, and polychlorinated dibenzofurans as endocrine disrupters--what we have learned from Yusho disease.多氯联苯、多氯二苯并对二恶英和多氯二苯并呋喃作为内分泌干扰物——我们从油症中学到的知识。
Environ Res. 2001 May;86(1):2-11. doi: 10.1006/enrs.2001.4244.
8
Workshop on perinatal exposure to dioxin-like compounds. IV. Neurobehavioral effects.围产期二噁英类化合物暴露研讨会。IV. 神经行为影响。
Environ Health Perspect. 1995 Mar;103 Suppl 2(Suppl 2):151-5. doi: 10.1289/ehp.95103s2151.
9
Risk assessments of polychlorinated dibenzo- p-dioxins, polychlorinated dibenzofurans, and dioxin-like polychlorinated biphenyls in food.食品中多氯代二苯并 - 对 - 二噁英、多氯代二苯并呋喃及类二噁英多氯联苯的风险评估
Mol Nutr Food Res. 2006 Oct;50(10):885-96. doi: 10.1002/mnfr.200500247.
10
Developmental neurotoxicity of dioxin and its related compounds.二噁英及其相关化合物的发育神经毒性。
Ind Health. 2003 Jul;41(3):215-30. doi: 10.2486/indhealth.41.215.
引用本文的文献
1
Dioxin-like Activity in Pregnant Women and Indices of Fetal Growth: The ACCEPT Birth Cohort.孕妇体内的二噁英样活性与胎儿生长指标：ACCEPT出生队列研究
Toxics. 2022 Jan 8;10(1):26. doi: 10.3390/toxics10010026.
2
Endocrine disruptors also function as nervous disruptors and can be renamed endocrine and nervous disruptors (ENDs).内分泌干扰物还具有神经干扰功能，可重新命名为内分泌和神经干扰物（ENDs）。
Toxicol Rep. 2021 Jul 31;8:1538-1557. doi: 10.1016/j.toxrep.2021.07.014. eCollection 2021.
3
Association between blood levels of PCDDs/PCDFs/dioxin-like PCBs and history of allergic and other diseases in the Japanese population.日本人群血液中 PCDDs/PCDFs/类二噁英 PCB 与过敏和其他疾病史的关联。
Int Arch Occup Environ Health. 2013 Nov;86(8):849-59. doi: 10.1007/s00420-012-0819-8. Epub 2012 Sep 27.
4
Increased proliferative effect of organochlorine compounds on human preadipocytes.有机氯化合物对人前体脂肪细胞增殖作用的增强。
Mol Cell Biochem. 2012 Jun;365(1-2):275-8. doi: 10.1007/s11010-012-1268-0. Epub 2012 Feb 21.
5
Prevalence of metabolic syndrome associated with body burden levels of dioxin and related compounds among Japan's general population.日本普通人群中与二噁英及相关化合物身体负担水平相关的代谢综合征患病率。
Environ Health Perspect. 2009 Apr;117(4):568-73. doi: 10.1289/ehp.0800012. Epub 2008 Oct 10.
6
Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma.有机氯暴露、免疫基因变异与非霍奇金淋巴瘤风险
Blood. 2009 Feb 26;113(9):1899-905. doi: 10.1182/blood-2008-04-153858. Epub 2008 Dec 9.
7
AhR transcriptional activity in serum of Inuits across Greenlandic districts.格陵兰各地区因纽特人血清中的芳烃受体转录活性。
Environ Health. 2007 Oct 23;6:32. doi: 10.1186/1476-069X-6-32.
8
Dioxin-like activities in serum across European and Inuit populations.欧洲和因纽特人群血清中的二噁英样活性。
Environ Health. 2006 May 25;5:14. doi: 10.1186/1476-069X-5-14.
9
Characteristics and application of established luciferase hepatoma cell line that responds to dioxin-like chemicals.对二噁英类化学物质有反应的已建立的荧光素酶肝癌细胞系的特性及应用
World J Gastroenterol. 2003 Jul;9(7):1460-4. doi: 10.3748/wjg.v9.i7.1460.
10
Lessons from the polybrominated diphenyl ethers (PBDEs): precautionary principle, primary prevention, and the value of community-based body-burden monitoring using breast milk.多溴二苯醚（PBDEs）的教训：预防原则、一级预防以及利用母乳进行社区人体负荷监测的价值。
Environ Health Perspect. 2003 Jan;111(1):109-14. doi: 10.1289/ehp.5438.
本文引用的文献
1
Effects of perinatal exposure to specific PCB congeners on thyroid hormone concentrations and thyroid histology in the rat.围产期暴露于特定多氯联苯同系物对大鼠甲状腺激素浓度和甲状腺组织学的影响。
Toxicol Lett. 1993 Jun;68(3):311-23. doi: 10.1016/0378-4274(93)90023-q.
2
Effects of small doses of dioxins on the immune system of marmosets and rats.小剂量二噁英对狨猴和大鼠免疫系统的影响。
Ann N Y Acad Sci. 1993 Jun 23;685:662-86. doi: 10.1111/j.1749-6632.1993.tb35931.x.
3
Endometriosis in rhesus monkeys (Macaca mulatta) following chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.恒河猴（猕猴）长期暴露于2,3,7,8-四氯二苯并对二恶英后发生的子宫内膜异位症。
Fundam Appl Toxicol. 1993 Nov;21(4):433-41. doi: 10.1006/faat.1993.1119.
4
The neurochemical effects of PCB exposure are age-dependent.接触多氯联苯的神经化学效应具有年龄依赖性。
Arch Toxicol Suppl. 1994;16:128-37. doi: 10.1007/978-3-642-78640-2_15.
5
Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on humoral immunity and lymphocyte subpopulations: differences between mice and rats.2,3,7,8-四氯二苯并对二恶英（TCDD）对体液免疫和淋巴细胞亚群的影响：小鼠与大鼠的差异
Toxicol Appl Pharmacol. 1994 Feb;124(2):248-56. doi: 10.1006/taap.1994.1029.
6
Partial demasculinization and feminization of sex behavior in male rats by in utero and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin is not associated with alterations in estrogen receptor binding or volumes of sexually differentiated brain nuclei.雄性大鼠在子宫内和哺乳期暴露于2,3,7,8-四氯二苯并对二恶英后性行为出现部分去雄性化和雌性化，这与雌激素受体结合或性分化脑细胞核体积的改变无关。
Toxicol Appl Pharmacol. 1994 Aug;127(2):258-67. doi: 10.1006/taap.1994.1160.
7
Effects of in utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on responsiveness of the male rat reproductive system to testosterone stimulation in adulthood.子宫内及哺乳期暴露于2,3,7,8-四氯二苯并对二恶英对成年雄性大鼠生殖系统对睾酮刺激反应性的影响。
Toxicol Appl Pharmacol. 1994 Aug;127(2):250-7. doi: 10.1006/taap.1994.1159.
8
Delayed spatial alternation deficits resulting from perinatal PCB exposure in monkeys.
Arch Toxicol. 1988;62(4):267-73. doi: 10.1007/BF00332486.
9
Development after exposure to polychlorinated biphenyls and dichlorodiphenyl dichloroethene transplacentally and through human milk.经胎盘和通过母乳接触多氯联苯和二氯二苯二氯乙烯后的发育情况。
J Pediatr. 1988 Dec;113(6):991-5. doi: 10.1016/s0022-3476(88)80569-9.
10
Congenital poisoning by polychlorinated biphenyls and their contaminants in Taiwan.台湾地区多氯联苯及其污染物所致的先天性中毒
Science. 1988 Jul 15;241(4863):334-6. doi: 10.1126/science.3133768.
Zotero 插件