Spangler S K, Jacobs M R, Appelbaum P C
Department of Pathology (Clinical Microbiology), Hershey Medical Center, Pennsylvania 17033, USA.
J Clin Microbiol. 1995 May;33(5):1366-7. doi: 10.1128/jcm.33.5.1366-1367.1995.
The susceptibility of 201 anaerobes to erythromycin, azithromycin, clarithromycin, and roxithromycin was tested by agar dilution and E test methods by using a commercially available plate and dish system (OxyDish) to provide anaerobic conditions. Plates were incubated for 48 h. MICs for 50% of strains tested and MICs for 90% of strains tested by agar dilution and E test methods corresponded within 1 doubling dilution for all compounds. When all antibiotics were considered together, agar and E test MICs were within 1 and 2 doubling dilutions of each other in 84 to 91% and > 99% of cases, respectively.
采用琼脂稀释法和E试验法，使用市售平板和培养皿系统（OxyDish）提供厌氧条件，检测了201株厌氧菌对红霉素、阿奇霉素、克拉霉素和罗红霉素的敏感性。平板培养48小时。对于所有化合物，通过琼脂稀释法和E试验法测得的50%受试菌株的MIC以及90%受试菌株的MIC在1个稀释倍数内相符。当综合考虑所有抗生素时，琼脂法和E试验法测得的MIC在84%至91%的情况下相差1个稀释倍数以内，在超过99%的情况下相差2个稀释倍数以内。
