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合成代谢雄激素类固醇。当前问题。

Anabolic-androgenic steroids. Current issues.

作者信息

Yesalis C E, Bahrke M S

机构信息

Health Policy Science, College of Health and Human Development, Pennsylvania State University, University Park, USA.

出版信息

Sports Med. 1995 May;19(5):326-40. doi: 10.2165/00007256-199519050-00003.

Abstract

The use of drugs to enhance physical performance has been observed for thousands of years. Today, individuals continue to use a variety of substances, including anabolic-androgenic steroids, in the hope of enhancing their performance and appearance. Rumours persist regarding the incidence of the nonmedical use of anabolic steroids by athletes and nonathletes: however, true estimates are now available based on the results of systematic surveys. Although the vast majority of the athletic community accepts that anabolic steroids enhance performance and appearance, the extent to which this occurs and the factors influencing such effects remain incompletely understood and documented. Refinement of our knowledge of the ergogenic effects of anabolic steroids is not without merit; however, the existing scientific evidence coupled with an overwhelming number of anecdotal accounts argues against devoting significant resources to this area of investigation at present. The short term health effects of anabolic steroids have been increasingly studied and reviewed, and while anabolic steroid use has been associated with several adverse and even fatal effects, the incidence of serious effects thus far reported has been extremely low. The long term effects of anabolic steroid use are generally unknown. Unfortunately, the lack of scientific information on long term health effects has impeded, if not precluded, the formation of effective health education and drug abuse prevention strategies. Consequently, efforts should be expanded in the areas of prevention and education.

摘要

数千年来,人们一直观察到使用药物来提高身体机能的现象。如今,人们继续使用各种物质,包括合成代谢雄激素类固醇,以期提高自身机能和改善外表。关于运动员和非运动员非医疗使用合成代谢类固醇的发生率,谣言一直存在;不过,现在基于系统调查结果已有了确切估计。尽管绝大多数体育界人士都承认合成代谢类固醇能提高机能和改善外表,但这种情况发生的程度以及影响此类效果的因素仍未得到充分理解和记录。完善我们对合成代谢类固醇促力作用的认识并非毫无益处;然而,现有的科学证据以及大量传闻表明,目前不应将大量资源投入到这一研究领域。合成代谢类固醇的短期健康影响已得到越来越多的研究和审视,虽然使用合成代谢类固醇与多种不良甚至致命影响有关,但迄今为止报告的严重影响发生率极低。使用合成代谢类固醇的长期影响通常尚不清楚。不幸的是,缺乏关于长期健康影响的科学信息阻碍了(即便没有排除)有效健康教育和药物滥用预防策略的形成。因此,应在预防和教育领域加大力度。

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