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系统性淋巴结病作为卵巢浆液性表面乳头状癌的主要症状。

Systemic lymphadenopathy as the primary symptom of serous surface papillary carcinoma of the ovary.

作者信息

Chen C A, Huang S H, How S W, Hsieh C Y

机构信息

Department of Obstetrics and Gynecology, National Taiwan University Hospital, National Taiwan University Medical School, Taipei, Republic of China.

出版信息

Gynecol Oncol. 1995 Aug;58(2):251-4. doi: 10.1006/gyno.1995.1220.

DOI:10.1006/gyno.1995.1220
PMID:7622114
Abstract

Serous surface papillary carcinoma (SSPC) is a distinct type of ovarian cancer; most of the patients present with extensive intraabdominal disease at the time of diagnosis. In a 48-year-old patient with 6-month history of inguinal and then scalene lymphadenopathy, although series workup did not disclose any primary tumor, an exploratory laparotomy was performed because of the abnormally high serum CA-125 level (1024 U/ml) and the pathologic examination of the inguinal node suggesting an ovarian origin. At exploration, there was only a discernible SSPC lesion on the right ovary; no intraperitoneal spread but extensive lymph node metastasis was found. The patient died of disease 30 months after surgery, although adjuvant and salvage chemotherapy was given. Ovarian cancer should be part of the differential diagnosis in a woman with systemic lymphadenopathy but without any evidence of intraabdominal disease.

摘要

浆液性表面乳头状癌(SSPC)是一种独特类型的卵巢癌;大多数患者在诊断时已出现广泛的腹腔内病变。一名48岁女性患者有6个月腹股沟及随后斜角肌淋巴结肿大病史,尽管一系列检查未发现任何原发性肿瘤,但由于血清CA - 125水平异常升高(1024 U/ml)且腹股沟淋巴结病理检查提示起源于卵巢,遂行剖腹探查术。术中发现仅右侧卵巢有一个可辨认的SSPC病灶;无腹膜内播散,但发现广泛的淋巴结转移。尽管给予了辅助化疗和挽救性化疗,患者术后30个月死于该疾病。对于有全身淋巴结肿大但无腹腔内疾病证据的女性,卵巢癌应列入鉴别诊断范围。

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