德国关于引起甲癣的红色毛癣菌和须癣毛癣菌菌株抗菌药敏性的多中心研究结果。德国皮肤癣菌药物敏感性协作研究组。
Results of German multicenter study of antimicrobial susceptibilities of Trichophyton rubrum and Trichophyton mentagrophytes strains causing tinea unguium. German Collaborative Dermatophyte Drug Susceptibility Study Group.
作者信息
Korting H C, Ollert M, Abeck D
机构信息
Dermatologische Klinik, Ludwig-Maximilians-Universität, Munich, Germany.
出版信息
Antimicrob Agents Chemother. 1995 May;39(5):1206-8. doi: 10.1128/AAC.39.5.1206.
Abstract
Thirty-two strains of Trichophyton rubrum and 16 strains of Trichophyton mentagrophytes isolated from patients with tinea unguium in various parts of Germany were subjected to a microdilution test with six systemic or topical antimycotic agents. Apart from griseofulvin, there were no species-specific differences between the two species. Terbinafine was the most active antimycotic agent, with a MIC not exceeding 0.05 micrograms/ml.
摘要
从德国各地甲癣患者中分离出的32株红色毛癣菌和16株须癣毛癣菌，用六种全身或局部抗真菌药物进行了微量稀释试验。除灰黄霉素外，这两种菌之间没有种属特异性差异。特比萘芬是最有效的抗真菌药物，其最低抑菌浓度不超过0.05微克/毫升。
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