Cavaliere F, Pemberton J H, Cosimelli M, Fazio V W, Beart R W
Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA.
Dis Colon Rectum. 1995 Aug;38(8):807-12. doi: 10.1007/BF02049837.
This study was designed to determine functional outcomes and rates of survival and recurrence of coloanal anastomosis in rectal cancer patients.
Between 1981 and 1991, 117 patients underwent coloanal anastomosis. Fifteen percent of the patients had a J-pouch; the rest had a straight coloanal anastomosis. Thirty-eight percent had no diverting stoma. Median distance of the tumor from the anal verge was 6.7 cm.
Local recurrence rate was 7 percent. Five-year survival was fully 69 percent. Satisfactory fecal continence was achieved by 78 percent of patients; no J-pouch patient had frequent incontinence. Sixty-two percent of the patients had major (anastomotic leak = 18 percent) or minor complications; complications were not mitigated by a diverting stoma or worsened by adjuvant therapy.
Although coloanal anastomosis is associated with a high chance of complications, the long-term outcome, in terms of disease-free survival and satisfactory function, is excellent.
本研究旨在确定直肠癌患者结肠肛管吻合术的功能结局、生存率和复发率。
1981年至1991年间,117例患者接受了结肠肛管吻合术。15%的患者采用J形贮袋;其余患者采用直结肠肛管吻合术。38%的患者未行转流造口术。肿瘤距肛缘的中位距离为6.7厘米。
局部复发率为7%。五年生存率足有69%。78%的患者实现了满意的大便自控;没有J形贮袋患者有频繁失禁。62%的患者发生了严重(吻合口漏=18%)或轻微并发症;转流造口术并未减轻并发症,辅助治疗也未使其恶化。
尽管结肠肛管吻合术有较高的并发症发生几率,但就无病生存和满意功能而言,长期结局良好。