Robak T
II Klinika Chorób Wewnetrznych Akademii Medycznej w Lodzi.
Postepy Hig Med Dosw. 1994;48(5):565-87.
In the paper numerous activities of IL-6 toward various normal and neoplastic cells are reviewed. The role of this cytokine in pathophysiology of a various disease including infections and inflammatory and autoimmune diseases as well as in leukaemias, lymphomas and other neoplastic diseases is presented. Potential clinical value of the IL-6 levels in the serum and the role of its recombinant form in the treatment of thrombocytopenia and some neoplastic diseases is also discussed.
本文综述了白细胞介素-6（IL-6）对各种正常细胞和肿瘤细胞的多种作用。介绍了这种细胞因子在包括感染、炎症和自身免疫性疾病等多种疾病的病理生理学中的作用，以及在白血病、淋巴瘤和其他肿瘤性疾病中的作用。还讨论了血清中IL-6水平的潜在临床价值及其重组形式在治疗血小板减少症和某些肿瘤性疾病中的作用。
