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焦炉工人与职业相关的癌症风险:30年随访

Occupationally related cancer risk among coke oven workers: 30 years of follow-up.

作者信息

Costantino J P, Redmond C K, Bearden A

机构信息

Department of Biostatistics, University of Pittsburgh, PA 15261, USA.

出版信息

J Occup Environ Med. 1995 May;37(5):597-604. doi: 10.1097/00043764-199505000-00009.

Abstract

This study concerns the update of cause-specific mortality among coke oven workers. Updated information provides 3 decades of work history and vital status follow-up on 15,818 workers. Mortality patterns are summarized by race, cumulative exposure, and period of follow-up. The findings are consistent with those from earlier assessments, indicating that occupational exposure to coke oven emissions is associated with significant excess mortality from cancer of the respiratory system and of the prostate. Depending on the segment of the population considered, the respiratory cancer risk for coke oven workers ranged as high as 4.45 times that for non-oven workers. Relative risk values for cancer of the prostate ranged as high as 1.93. Rates of respiratory cancer across period of follow-up are declining, suggesting that the implementation of emissions control and occupational exposure limits has been beneficial.

摘要

本研究关注焦炉工人特定病因死亡率的更新情况。更新后的信息提供了15818名工人长达30年的工作史及生命状况随访数据。死亡率模式按种族、累积暴露量和随访期进行总结。研究结果与早期评估一致,表明职业性接触焦炉排放物与呼吸系统癌症和前列腺癌的显著超额死亡率相关。根据所考虑的人群分组,焦炉工人患呼吸道癌症的风险比非焦炉工人高至4.45倍。前列腺癌的相对风险值高至1.93。随访期间呼吸道癌症发病率呈下降趋势,表明实施排放控制和职业暴露限值是有益的。

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