Tsetsonis N V, Hardman A E
Department of Physical Education, Loughborough University of Technology, Leicestershire, England.
Eur J Appl Physiol Occup Physiol. 1995;70(4):329-36. doi: 10.1007/BF00865030.
The purpose of the present study was to compare the acute and delayed effects of low- and moderate-intensity exercise on serum lipoprotein concentrations. Twelve healthy volunteers (five men, seven women), aged 28 (2) years [mean (SEM)], maximal oxygen uptake (VO2max) 48 (3) ml.kg-1.min-1 walked on a treadmill for 90 min, on two separate occasions, in a balanced design. On one occasion walking was at a grade which elicited 32.1 (0.8)% of VO2max, i.e. low intensity, while on the other it elicited 60.1 (1.6)% of VO2max, i.e. moderate intensity (MI). Serum concentrations of total cholesterol (TC), triacylglycerol (TAG), high density lipoprotein cholesterol (HDL-C) and the subfraction HDL2-C free fatty acids (FFA) and free glycerol were measured in venous blood samples drawn before exercise (after a 12-h fast), during walking and after 1 h and 24 h of recovery. Serum TAG concentrations decreased as a result of the exercise bout over the period of observation (P < 0.05), but this decrease was not different between the two intensities. Changes in serum TC concentrations over time differed between trials (P < 0.05). Serum free glycerol and FFA concentrations increased during exercise bouts, these increases being (P < 0.05) greater with MI. The decrease in serum TAG concentrations during and after a single episode of either prolonged low or moderate intensity exercise may be associated with an increased clearance and/or a decreased secretion of TAG-rich lipoproteins.
本研究的目的是比较低强度和中等强度运动对血清脂蛋白浓度的急性和延迟影响。12名健康志愿者（5名男性，7名女性），年龄28（2）岁[均值（标准误）]，最大摄氧量（VO2max）为48（3）ml·kg-1·min-1，在跑步机上以平衡设计分两次各步行90分钟。一次步行的坡度能引发VO2max的32.1（0.8）%，即低强度，另一次能引发VO2max的60.1（1.6）%，即中等强度（MI）。在运动前（禁食12小时后）、步行期间以及恢复1小时和24小时后采集的静脉血样本中，测量总胆固醇（TC）、三酰甘油（TAG）、高密度脂蛋白胆固醇（HDL-C）及其亚组分HDL2-C、游离脂肪酸（FFA）和游离甘油的血清浓度。在观察期内，运动使血清TAG浓度降低（P<0.05），但两种强度之间的降低无差异。不同试验中血清TC浓度随时间的变化不同（P<0.05）。运动期间血清游离甘油和FFA浓度升高，中等强度时升高幅度更大（P<0.05）。单次长时间低强度或中等强度运动期间及之后血清TAG浓度的降低可能与富含TAG的脂蛋白清除增加和/或分泌减少有关。
