Garnham P C, Bray R S, Bruce-Chwatt L J, Draper C C, Killick-Kendrick R, Sergiev P G, Tiburskaja N A, Shute P G, Maryon M
Bull World Health Organ. 1975;52(1):21-32.
Numerous strains of P. vivax, distinguishable chiefly by their biological characteristics, are known to exist. Two main varieties are recognized: the so-called temperate and tropical strains. The most extreme example of the former-designated by Nikolaev as P. vivax hibernans-constantly exhibited an extremely long incubation period. The strain is no longer in existence and no type material has been preserved. In its place, a North Korean strain with a generally long incubation period has been studied and compared with the well-known tropical Madagascar strain, which frequently but not constantly has a short incubation period. The data presented here concern the behaviour of various strains from the USSR and the morphological characteristics of the North Korean and Madagascar strains. Splenectomized chimpanzees were used as the host of these parasites, particularly in regard to exoerythrocytic schizogony. Attempts were also made, by late biopsies of the liver of the apes, to elucidate the prolonged latency of the North Korean strain. Although there was no evidence of specifically dormant forms, it is probable that certain sporozoites fail to develop in the normal time and that they are reactivated by an unknown factor a year or more after inoculation.
已知存在许多间日疟原虫菌株，主要通过其生物学特性加以区分。公认有两个主要变种：即所谓的温带菌株和热带菌株。前者最极端的例子——被尼古拉耶夫命名为间日疟原虫蛰伏亚种——始终表现出极长的潜伏期。该菌株已不复存在，且未保存类型材料。取而代之的是，对一种潜伏期普遍较长的朝鲜菌株进行了研究，并与著名的热带马达加斯加菌株进行了比较，后者的潜伏期通常较短，但并非总是如此。本文提供的数据涉及来自苏联的各种菌株的行为以及朝鲜和马达加斯加菌株的形态特征。切除脾脏的黑猩猩被用作这些寄生虫的宿主，特别是在关于红细胞外裂体增殖方面。还通过对猿类肝脏进行晚期活检，试图阐明朝鲜菌株潜伏期延长的原因。尽管没有证据表明存在特定的休眠形式，但很可能某些子孢子未能在正常时间内发育，并且它们在接种一年或更长时间后被未知因素重新激活。
