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环孢素A治疗对皮质类固醇-硫唑嘌呤耐药的自身免疫性肝炎

Treatment of corticosteroid-azathioprine resistant autoimmune hepatitis with cyclosporin A.

作者信息

Senturk H

机构信息

Department of Internal Medicine, Cerrahpasa Medical Faculty of Istanbul University, Turkey.

出版信息

Indian J Gastroenterol. 1995 Jul;14(3):110-1.

PMID:7657365
Abstract

A 33-year-old woman with autoimmune hepatitis developed resistance to prednisolone-azathioprine treatment. A switch to cyclosporin A resulted in immediate remission which was maintained for more than one year. No significant side effect was encountered. Cyclosporin A may be an alternative treatment for patients with autoimmune hepatitis who are resistant to conventional treatment.

摘要

一名33岁的自身免疫性肝炎女性患者对泼尼松龙 - 硫唑嘌呤治疗产生了耐药性。改用环孢素A后病情立即缓解,并持续了一年多。未出现明显副作用。对于对传统治疗耐药的自身免疫性肝炎患者,环孢素A可能是一种替代治疗方法。

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