Lewis-Jones M S, Finlay A Y
Department of Dermatology, Wrexham Maelor Hospital, Clwyd, U.K.
Br J Dermatol. 1995 Jun;132(6):942-9. doi: 10.1111/j.1365-2133.1995.tb16953.x.
Skin disease can cause severe disability and handicap in children. Measurement of the impact of skin disease on the quality of life is required to aid clinical decision-making, for clinical research, for audit of paediatric dermatology services, and for political reasons, to aid arguments for more resources for the care of children with skin disease. Adult measures are inappropriate, as the lives of children differ markedly from those of adults. The purpose of this study was to create and initially validate a simple practical questionnaire for use in children. One hundred and sixty-nine children, aged 3-16 years, attending a paediatric dermatology clinic, wrote down, with the help of their parents, all the ways in which their skin disease affected their lives. One hundred and eleven different aspects were identified; 10 questions were composed to cover these aspects, using a structure similar to the Adult Dermatology Life Quality Index. This draft questionnaire was piloted on two series, totalling 40 children, and minor alterations were made to improve clarity. The Children's Dermatology Life Quality Index (CDLQI) questionnaire (maximum score 30) was then given to a further 233 dermatology paediatric out-patients (CDLQI mean = 5.1, SD = 4.9), 47 normal controls (mean 0.4, 0.7) and 55 control patients attending a general paediatric clinic (mean 0.7, 2.5). The CDLQI scores for eczema (mean = 7.7, 5.6, n = 47), psoriasis (5.4, 5.0, n = 25) and acne (5.7, 4.4, n = 40), were all highly significantly greater than for moles and naevi (2.3, 2.9, n = 29). The highest mean score was that for scabies (mean = 9.5, 10.5, n = 6).(ABSTRACT TRUNCATED AT 250 WORDS)
皮肤疾病会导致儿童严重的残疾和障碍。为了辅助临床决策、进行临床研究、审核儿科皮肤科服务以及出于政治原因（为争取更多资源用于照顾患皮肤疾病的儿童提供依据），需要衡量皮肤疾病对生活质量的影响。成人的衡量方法并不适用，因为儿童的生活与成人明显不同。本研究的目的是创建并初步验证一种适用于儿童的简单实用问卷。169名年龄在3至16岁之间、前往儿科皮肤科诊所就诊的儿童，在其父母的帮助下，写下了他们的皮肤疾病影响生活的所有方式。共识别出111个不同方面；使用与成人皮肤病生活质量指数类似的结构，编写了10个问题来涵盖这些方面。这份问卷初稿在总共40名儿童的两个系列中进行了试用，并做了一些小的修改以提高清晰度。然后，将儿童皮肤病生活质量指数（CDLQI）问卷（最高分30分）发给另外233名儿科皮肤科门诊患者（CDLQI平均值 = 5.1，标准差 = 4.9）、47名正常对照儿童（平均值0.4，标准差0.7）以及55名前往普通儿科诊所就诊的对照患者（平均值0.7，标准差2.5）。湿疹患者（平均值 = 7.7，标准差5.6，n = 47）、银屑病患者（5.4，5.0，n = 25）和痤疮患者（5.7，4.4，n = 40）的CDLQI得分均显著高于痣和色素痣患者（2.3，2.9，n = 29）。平均得分最高的是疥疮患者（平均值 = 9.5，标准差10.5，n = 6）。（摘要截选至250词）
