Mladenovic I, Micic S, Pearson R M, Genbacev O, Papic N
Institute for the Application of Nuclear Energy--INEP, Belgrade, Yugoslavia.
J Assist Reprod Genet. 1994 Nov;11(10):495-9. doi: 10.1007/BF02216028.
Pentoxifylline was tested in three raising concentrations (0.7 mM/l, 1.5 mM/l, 3.6 mM/l) on human sperm cells in vitro.
On 143 samples, we examined drug effect on motile sperm concentration, grade of their motility, acrosome reaction and membrane status.
Obtained results show improvement in motile sperm concentration, as well as in the grade of progression in the majority of samples.
Spermatozoa membranes as well as occurrence of the acrosomal reaction were not affected by pentoxifylline.