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1975 - 1992年英格兰和威尔士原发性肝癌死亡率趋势:口服避孕药的影响

Trends in mortality from primary liver cancer in England and Wales 1975-92: influence of oral contraceptives.

作者信息

Mant J W, Vessey M P

机构信息

Department of Public Health and Primary Care, University of Oxford, Radcliffe Infirmary, UK.

出版信息

Br J Cancer. 1995 Sep;72(3):800-3. doi: 10.1038/bjc.1995.415.

DOI:10.1038/bjc.1995.415
PMID:7669599
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2033882/
Abstract

Numerous case-control studies have suggested a link between the oral contraceptive pill and liver cancer. The secular trends in liver cancer mortality rates for England and Wales from 1975 to 1992 were examined to determine whether an effect of the pill was apparent. Liver cancer mortality has remained constant in women in the age groups that have had major exposure to the pill.

摘要

众多病例对照研究表明口服避孕药与肝癌之间存在联系。对1975年至1992年英格兰和威尔士肝癌死亡率的长期趋势进行了研究,以确定避孕药的影响是否明显。在大量接触过避孕药的年龄组女性中,肝癌死亡率一直保持稳定。

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本文引用的文献

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Br J Cancer. 1993 Mar;67(3):635-7. doi: 10.1038/bjc.1993.116.
2
Oral contraceptive use and mortality during 12 years of follow-up: the Nurses' Health Study.12年随访期间口服避孕药的使用与死亡率:护士健康研究
Ann Intern Med. 1994 May 15;120(10):821-6. doi: 10.7326/0003-4819-120-10-199405150-00002.
3
Trends in mortality from carcinoma of the liver and the use of oral contraceptives.肝癌死亡率趋势与口服避孕药的使用情况
Br J Cancer. 1983 Sep;48(3):349-54. doi: 10.1038/bjc.1983.199.
4
Hepatocellular carcinoma and oral contraceptives.肝细胞癌与口服避孕药
Br J Cancer. 1983 Sep;48(3):437-40. doi: 10.1038/bjc.1983.210.
5
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6
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Br Med J (Clin Res Ed). 1986 May 24;292(6532):1355-7. doi: 10.1136/bmj.292.6532.1355.
7
Oral contraceptives and primary liver cancer.口服避孕药与原发性肝癌
Br J Cancer. 1989 Mar;59(3):460-1. doi: 10.1038/bjc.1989.94.
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Br J Obstet Gynaecol. 1989 Jul;96(7):783-8. doi: 10.1111/j.1471-0528.1989.tb03316.x.
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