Polosukhin V V, Egunova S M, Chuvakin S G, Bessonov A P
Vestn Ross Akad Med Nauk. 1995(7):48-53.
Structural and metabolic changes were studied in 162 large bronchial mucosa biopsy specimens from 63 patients with chronic lung diseases. Proliferative and metabolic processes were shown to be induced by endotracheal therapy with helium-neon laser for the damaged epithelium, which passed through a number of transitional forms and repaired its structure and differentiation into ciliary and goblet cells with normal ultrastructure. In lamina propria, there was hyperemia, intensive leukodiapedesis, formation of leukocytic infiltrated and granulations, the metabolic activity of endotheliocytes and interstitial cells increased, giving rise to delicate fibrous connective tissue. The simultaneous reorganization of the epithelium and underlying connective tissue is interpreted from the standpoint of a concept of parenchymal and stromal relationships.
对63例慢性肺部疾病患者的162份大支气管黏膜活检标本进行了结构和代谢变化研究。结果显示，氦氖激光气管内治疗可诱导受损上皮的增殖和代谢过程，上皮经历了多种过渡形式，修复了其结构，并分化为具有正常超微结构的纤毛细胞和杯状细胞。在固有层，出现了充血、白细胞大量渗出、白细胞浸润和肉芽形成，内皮细胞和间质细胞的代谢活性增加，产生了纤细的纤维结缔组织。从实质与间质关系的概念角度解释了上皮和其下方结缔组织的同时重组。
