Murphy J C, Kaden D A, Warren J, Sivak A
Health Effects Institute, Cambridge, MA 02139.
Mutat Res. 1993 Mar;296(3):221-40. doi: 10.1016/0165-1110(93)90013-d.
Epidemiologic studies have reported a modestly increased risk of childhood leukemia associated with certain electric power wire configurations. Since cancer likely involves DNA damage, this review discusses the evidence of direct and indirect genetic toxicity effects for both electric and magnetic fields at 50- and 60-Hz and miscellaneous pulsed exposures. Exposure conditions vary greatly among different end points measured, making comparisons and conclusions among experiments difficult. Although most of the available evidence does not suggest that electric and/or magnetic fields cause DNA damage, the existence of some positive findings and limitations in the set of studies carried out suggest a need for additional work.
流行病学研究报告称，某些电线配置与儿童白血病风险略有增加有关。由于癌症可能涉及DNA损伤，本综述讨论了50赫兹和60赫兹的电场和磁场以及各种脉冲暴露对遗传毒性产生直接和间接影响的证据。不同测量终点的暴露条件差异很大，这使得实验之间的比较和结论变得困难。尽管现有大多数证据并不表明电场和/或磁场会导致DNA损伤，但已开展的一系列研究中存在一些阳性结果和局限性，这表明有必要开展更多工作。
