Lacour J P, Bodokh I, Castanet J, Bekri S, Ortonne J P
Department of Dermatology, University of Nice, France.
Br J Dermatol. 1993 Feb;128(2):121-3. doi: 10.1111/j.1365-2133.1993.tb15139.x.
We have studied the prevalence of hepatitis C virus antibodies (anti-HCV) in 13 patients suffering from sporadic porphyria cutanea tarda. The sera were tested by Abbott second-generation enzyme immunoassay; seropositivity was confirmed by Ortho second-generation recombinant immunoblot assay. Ten cases (76.1%) were anti-HCV positive; one patient was also seropositive for HIV. This preliminary study suggests that HCV could be a frequent triggering factor for sporadic porphyria cutanea tarda.
我们研究了13例迟发性皮肤卟啉病患者丙型肝炎病毒抗体(抗-HCV)的流行情况。血清通过雅培第二代酶免疫测定法进行检测;血清阳性通过奥索第二代重组免疫印迹测定法得以确认。10例(76.1%)抗-HCV呈阳性;1例患者HIV血清也呈阳性。这项初步研究表明,HCV可能是迟发性皮肤卟啉病常见的触发因素。