Lev A A, Korchev Y E, Rostovtseva T K, Bashford C L, Edmonds D T, Pasternak C A
Institute of Cytology, Academy of Sciences, St Petersburg, Russia.
Proc Biol Sci. 1993 Jun 22;252(1335):187-92. doi: 10.1098/rspb.1993.0064.
Ions flowing through purely synthetic filters made of polyethylene terephthalate which have been etched to produce narrow pores show: (i) rapid transitions between a high-conducting and a low-conducting state; (ii) selectivity of ion flow; and (iii) inhibition by divalent cations and protons. These features resemble those displayed by many biological ion channels. We interpret our results in terms of the special properties of ion conductance at an interface that may be observed whenever the contribution of bulk conductance is minimal.
离子流经由聚对苯二甲酸乙二酯制成的纯合成过滤器，这些过滤器经过蚀刻以产生狭窄的孔隙，结果显示：（i）在高导电状态和低导电状态之间的快速转变；（ii）离子流的选择性；以及（iii）被二价阳离子和质子抑制。这些特征类似于许多生物离子通道所表现出的特征。我们根据界面处离子电导的特殊性质来解释我们的结果，只要体电导的贡献最小，就可能观察到这种特殊性质。
