Martelletti P, Granata M, Giacovazzo M
Headache Centre, University La Sapienza, Rome, Italy.
Cephalalgia. 1993 Oct;13(5):343-5; discussion 307-8. doi: 10.1046/j.1468-2982.1993.1305343.x.
We measured serum interleukin-1 beta (IL-1 beta) in 24 episodic cluster headache (CH) patients and 45 normal controls using a specific ELISA method. There was an increase in IL-1 beta in all CH patients compared to controls. IL-1 beta was further increased during the ictal phase of CH compared to patients between attacks and normal individuals. Between attacks, IL-1 beta was also significantly increased compared to controls. We suggest that these results represent an activation of the immune system in CH.
我们使用特定的酶联免疫吸附测定（ELISA）方法，对24例发作性丛集性头痛（CH）患者和45名正常对照者的血清白细胞介素-1β（IL-1β）进行了测量。与对照组相比，所有CH患者的IL-1β均有所升高。与发作间期的患者及正常个体相比，CH发作期的IL-1β进一步升高。在发作间期，与对照组相比，IL-1β也显著升高。我们认为这些结果表明CH患者的免疫系统被激活。
