Fielding D I, McKeon J L, Oliver W A, Matar K, Brown I G
Department of Thoracic Medicine, Prince Charles Hospital, Chermside, Brisbane, Queensland, Australia.
Thorax. 1995 Feb;50(2):181-3. doi: 10.1136/thx.50.2.181.
Persistent severe pain is a rare complication of benign asbestos-related pleural disease.
Four patients are described in whom pain persisted for more than one year (range 18 months to five years) which was incompletely relieved by opioid medication and nerve blocking procedures. All underwent pleurectomy in an attempt to relieve it.
At operation the pleura was considerably thickened in all cases. Two of the four patients had successful relief of pain. The other two had a neuralgic component to their pain before surgery which persisted afterwards. One of these patients underwent successful cervical cordotomy.
Pleurectomy may provide relief in patients with constant pleuritic pain due to benign asbestos-related pleural thickening. It seems, however, that patients in whom the pain has a neuralgic component are unlikely to benefit.
持续性剧痛是良性石棉相关胸膜疾病的一种罕见并发症。
描述了4例疼痛持续超过1年(范围为18个月至5年)的患者,阿片类药物和神经阻滞手术未能完全缓解其疼痛。所有患者均接受了胸膜切除术以缓解疼痛。
手术时,所有病例的胸膜均显著增厚。4例患者中有2例疼痛得到成功缓解。另外2例患者术前疼痛有神经痛成分,术后仍持续存在。其中1例患者接受了成功的颈髓切断术。
胸膜切除术可能会缓解因良性石棉相关胸膜增厚引起的持续性胸膜炎性疼痛患者的症状。然而,疼痛有神经痛成分的患者似乎不太可能从中受益。