Villarejos V M, Anderson-Visoná K, Canales J S
Am J Trop Med Hyg. 1978 Mar;27(2 Pt 1):286-9. doi: 10.4269/ajtmh.1978.27.286.
The correlation between transmission of e-antigen (e-Ag) and hepatitis B antigen (HBsAg) was investigated in primary and secondary cases of type B hepatitis occurring in 15 families. The e-Ag was not consistently transmitted in the familial environment, as were the d and y subtypes of HBsAg, but occurred in erratic fashion among genetically and epidemiologically related cases. It is concluded that e-Ag is probably the non-transmissible product of a specific individual response to hepatitis B infection.
对15个家庭中出现的乙型肝炎原发和继发病例,研究了e抗原(e-Ag)与乙肝表面抗原(HBsAg)传播之间的相关性。e-Ag不像HBsAg的d和y亚型那样在家庭环境中持续传播,而是在遗传和流行病学相关的病例中以不稳定的方式出现。结论是,e-Ag可能是对乙肝感染的特定个体反应的不可传播产物。