Rivera J A, Martorell R, Ruel M T, Habicht J P, Haas J D
Centro de Investigaciones en Salud Pública, Instituto Nacional de Salud Pública, Morelos, Mexico.
J Nutr. 1995 Apr;125(4 Suppl):1068S-1077S. doi: 10.1093/jn/125.suppl_4.1068S.
Effects of supplementary feeding during early childhood on body size and composition at adolescence are examined in a population with marked growth failure in the first 3 y of life. The data came from a supplementation trial conducted in rural Guatemala from 1969 to 1977 and a 1988-89 follow-up study of the same subjects at adolescence. Two pairs of villages participated in the trial. One village from each pair received a high protein-energy supplement (Atole), which significantly improved dietary intakes, whereas the other village of the pair received a low-energy, no-protein supplement (Fresco), which did not impact appreciably on dietary intakes. Children from Atole villages grew better during the preschool period than children from Fresco villages. At adolescence, subjects from Atole villages were taller, weighed more and had greater fat-free masses than subjects from Fresco villages. Differences in height at adolescence were slightly reduced in magnitude relative to differences at 3 y of age. However, differences in weight were increased in adolescence relative to 3 y of age.
在生命最初3年有明显生长发育迟缓的人群中，研究了幼儿期补充喂养对青春期时体型和身体组成的影响。数据来自1969年至1977年在危地马拉农村进行的一项补充试验，以及1988 - 1989年对同一批受试者青春期时的随访研究。两对村庄参与了该试验。每对中的一个村庄接受高蛋白能量补充剂（阿托尔），这显著改善了饮食摄入量，而另一对中的另一个村庄接受低能量、无蛋白质补充剂（弗雷斯可），这对饮食摄入量没有明显影响。来自阿托尔村庄的儿童在学龄前比来自弗雷斯可村庄的儿童生长得更好。在青春期，来自阿托尔村庄的受试者比来自弗雷斯可村庄的受试者更高、体重更重且去脂体重更大。青春期时身高的差异相对于3岁时的差异在幅度上略有减小。然而，青春期时体重的差异相对于3岁时有所增加。
