Jonniaux J L, Coster F, Purnelle B, Goffeau A
Unité de Biochimie Physiologique, Université Catholique de Louvain, Louvain-la-Neuve, Belgium.
Yeast. 1994 Dec;10(12):1639-45. doi: 10.1002/yea.320101213.
We report the amino acid sequence of 13 open reading frames (ORF > 299 bp) located on a 21.7 kb DNA segment from the left arm of chromosome XIV of Saccharomyces cerevisiae. Five open reading frames had been entirely or partially sequenced previously: WHI3, GCR2, SPX19, SPX18 and a heat shock gene similar to SSB1. The products of 8 other ORFs are new putative proteins among which N1394 is probably a membrane protein. N1346 contains a leucine zipper pattern and the corresponding ORF presents an HAP (global regulator of respiratory genes) upstream activating sequence in the promoting region. N1386 shares homologies with the DNA structure-specific recognition protein family SSRPs and the corresponding ORF is preceded by an MCB (MluI cell cycle box) upstream activating factor.
我们报道了位于酿酒酵母第十四条染色体左臂上一个21.7 kb DNA片段上的13个开放阅读框（ORF > 299 bp）的氨基酸序列。其中5个开放阅读框先前已被全部或部分测序：WHI3、GCR2、SPX19、SPX18以及一个与SSB1相似的热休克基因。其他8个ORF的产物是新的假定蛋白，其中N1394可能是一种膜蛋白。N1346含有亮氨酸拉链模式，相应的ORF在启动子区域呈现一个HAP（呼吸基因全局调节因子）上游激活序列。N1386与DNA结构特异性识别蛋白家族SSRP具有同源性，相应的ORF之前有一个MCB（MluI细胞周期框）上游激活因子。
