头孢丙烯与13种口服头孢菌素及3种大环内酯类药物的抗菌活性比较。
Antibacterial activities of cefprozil compared with those of 13 oral cephems and 3 macrolides.
作者信息
Fung-Tomc J C, Huczko E, Stickle T, Minassian B, Kolek B, Denbleyker K, Bonner D, Kessler R
机构信息
Bristol-Myers Squibb Pharmaceutical Research Institute, Wallingford, Connecticut 06492, USA.
出版信息
Antimicrob Agents Chemother. 1995 Feb;39(2):533-8. doi: 10.1128/AAC.39.2.533.
Abstract
Thirteen oral cephems (cefprozil, loracarbef, cefaclor, cefuroxime axetil, cefpodoxime proxetil, cefetamet pivoxil, cefixime, cefdinir, cefadroxil, cephradine, cephalexin, cefatrizine, and cefroxadine), the cephalosporin class representative cephalothin, cefazolin, and the macrolides erythromycin, clarithromycin, and azithromycin were compared for their antibacterial activities against 790 recent clinical isolates. These oral agents differed in their spectra and antibacterial potencies against community-acquired pathogens.
摘要
对13种口服头孢菌素（头孢丙烯、氯碳头孢、头孢克洛、头孢呋辛酯、头孢泊肟酯、头孢他美酯、头孢克肟、头孢地尼、头孢羟氨苄、头孢拉定、头孢氨苄、头孢曲嗪和头孢沙定）、头孢菌素类代表性药物头孢噻吩、头孢唑林以及大环内酯类药物红霉素、克拉霉素和阿奇霉素针对790株近期临床分离菌株的抗菌活性进行了比较。这些口服药物在针对社区获得性病原体的抗菌谱和抗菌效力方面存在差异。
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